Issue Highlights

Abstract

Gastrointestinal symptoms and liver injury are not uncommon in patients with coronavirus disease 2019 . The empirical use of Chinese herbal medicine (CHM) during COVID-19 has received noticeable attention. This meta-analysis critically appraising CHM seemingly indicated that the advantage of CHM as an adjuvant showed more on reducing the rate of COVID-19 aggravation and nucleic acid-negative conversion time to treat the emergency symptoms, than improving gastrointestinal symptoms and liver function, based on the latest evidence. Our findings underlined the need of paying attention to COVID-19 patients suffering gastrointestinal symptoms and liver injury, which may inspire the development of new drugs. 800 Netrin-1 and clusterin: Innovative potential diagnostic biomarkers for early renal damage in β-thalassemia major children