Abstract:Introduction: Conventional phlebotomy is the standard therapy to remove either erythrocytes or iron in patients with Polycythema Vera (and sec. polyglobulinemia) or patients with hemochromatosis (HC) (and iron overload). This treatment that should be repeated regular has its side effects, is often experienced as inconvenient by the patients and the desired effect is not always reached. We developed an erythrocytapheresis technique based on an isovolemic principle that can be used to remove larger amounts of er… Show more
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