Abstract:Isotretinoin is a derivative of vitamin A (13-cis retinoic acid) and represents the first generation of retinoids. It affects all the key factors in the pathogenesis of acne and all current guidelines agree that it is still the most effective therapeutic option in the treatment of acne. In addition to conventional treatment, the modern concept of treatment allows various other protocols, so proper selection of patients and adjustment of isotretinoin treatment modality to the type and severity of acne is necess… Show more
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