Isotope Quantitation of Aortic Insufficiency Compared to Cineangiography in Man

Hildner, Frank J.; Pierson, William R.; Barold, S. Serge; Linhart, Joseph W.; Samet, Philip

doi:10.1016/s0003-4975(10)66413-2

Cited by 9 publications

(1 citation statement)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Human serum albumin labeled with 99mTc has been administered into a peripheral vein (1,2), and via catheters into the pulmonary artery (3,4) or left ventricle (5). The circulation of this intravascular tracer may be monitored with the aid of a scintillation camera interfaced with a computer, and quantitative estimates made of the following cardiac parameters: (~) cardiac output (4); (b) mean central transit time (6)(7)(8); (c) left ventricular ejection fraction (9); and (d) regurgitant fraction (9).…”

mentioning

confidence: 99%

A Noninvasive Technique for the Study of Cardiac Hemodynamics Utilizing C¹⁵O₂Inhalation

Watson

Kenny

Gelband³

et al. 1976

Radiology

Self Cite

View full text Add to dashboard Cite

A new technique for the study of cardiac hemodynamics is described which utilizes single-breath inhalation of C15O2 (T 1/2 = 124 sec.) and the recording of activity vs. time curves with scintillation counters placed externally over the left ventricle and right lung. The results from 10 normal volunteers and 28 patients with acquired or congenital heart disease have been compared to the findings at cardiac catheterization. The technique is safe, rapid, and nontraumatic, and yielded no false positives or negatives in this series.

show abstract

mentioning

confidence: 99%

A Noninvasive Technique for the Study of Cardiac Hemodynamics Utilizing C¹⁵O₂Inhalation

Watson

Kenny

Gelband³

et al. 1976

Radiology

Self Cite

View full text Add to dashboard Cite

show abstract

Evaluation of aortic and mitral valve regurgitation by radionuclide ventriculography: Comparison with the method of sandler and dodge

Kress

Geffers

Stauch

et al. 1981

Clinical Cardiology

View full text Add to dashboard Cite

The present investigation was undertaken to introduce a quantitative scintigraphic method for evaluation of regurgitation and to compare it with the generally accepted quantitative method of Sandler and Dodge (Sandler et al., 1963). Radionuclide ventriculography was carried out after injection of 20 mCi 99mtechnetium-labeled red blood cells. Time-activity curves were obtained from the left and right ventricular regions. The ratio (A) of end-diastolic-end-systolic count-rate differences for the left and right ventricles was calculated. The ratio (A) was compared with a hemodynamic ratio (Ah) determined after the method of Sandler and Dodge (1963) with the stroke volume of the left ventricle measured angiographically, and the stroke volume of the right ventricle measured by thermodilution. In 33 patients with aortic and mitral valve regurgitation we found a correlation of r = 0.75 between (A) and Ah). Due to a broad range of normal values of (A) the sensitivity of the scintigraphic method is low. The specificity seems to be high, however, since in 64 patients with all types of heart diseases there were no false positive results. Comparing the described scintigraphic method with other modern or generally accepted methods, the principal advantages are noninvasiveness, good practicability, and the fact that important additional information about the functional state of the heart is gained. This is important in follow-up studies in patients with chronic valvular incompetence. It seems that this method will become a valuable supplement to heart catheterization in the diagnosis of valvular heart disease and may partially replace invasive methods for measuring the regurgitation fraction.

show abstract

Quantitation of Aortic Regurgitation

Eichhorn¹,

Konstam²

1988

Developments in Cardiovascular Medicine

View full text Add to dashboard Cite

Isotope Quantitation of Aortic Insufficiency Compared to Cineangiography in Man

Cited by 9 publications

References 12 publications

A Noninvasive Technique for the Study of Cardiac Hemodynamics Utilizing C¹⁵O₂Inhalation

A Noninvasive Technique for the Study of Cardiac Hemodynamics Utilizing C¹⁵O₂Inhalation

Evaluation of aortic and mitral valve regurgitation by radionuclide ventriculography: Comparison with the method of sandler and dodge

Quantitation of Aortic Regurgitation

Contact Info

Product

Resources

About

Isotope Quantitation of Aortic Insufficiency Compared to Cineangiography in Man

Cited by 9 publications

References 12 publications

A Noninvasive Technique for the Study of Cardiac Hemodynamics Utilizing C15O2Inhalation

A Noninvasive Technique for the Study of Cardiac Hemodynamics Utilizing C15O2Inhalation

Evaluation of aortic and mitral valve regurgitation by radionuclide ventriculography: Comparison with the method of sandler and dodge

Quantitation of Aortic Regurgitation

Contact Info

Product

Resources

About

A Noninvasive Technique for the Study of Cardiac Hemodynamics Utilizing C¹⁵O₂Inhalation

A Noninvasive Technique for the Study of Cardiac Hemodynamics Utilizing C¹⁵O₂Inhalation