“…According to the Ecological and Toxicological Association of the Dyestuffs Manufacturing Industry investigation of 4,000 kinds of dyes on the market, the half lethal dose value of over 90% of them is 2×10 3 mg/kg, where basic dyes and diazo direct dyes have the highest toxicity [26], [27]. In addition, there are more than 100 thousand kinds of dyes on the global market, where the total output is as high as 700 thousand MT/year [22], [28]- [30], as dyes are universally used in many industries, such as textile, paper-making, leather, food, printing, [22], [23], [30], [31]. The paper industry is the second largest user of dyes in the U.S., where ordinary colored paper accounts for 40%, primary pulp paper accounts for 20%, color card paper accounts for 20%, and medical paper accounts for 10%.…”