Isopropyl alcohol is as efficient as chlorhexidine to prevent contamination of blood cultures

Martínez, Jovanna; Macias, Juan H.; Arreguín, Virginia; Álvarez, José Antonio; Macías, Alejandro E.; Mosqueda, Juan L.

doi:10.1016/j.ajic.2016.11.027

Cited by 14 publications

(8 citation statements)

References 14 publications

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“…The low basal rate of contamination (0.76%) and the use of phlebotomy carts may have biased the results. Other authors did not find any significant difference between the BCC rates comparing CHG to 2% iodine tincture [57] or alcohol alone to 2% alcoholic CHG [58]. It is difficult to make a recommendation because some of these studies lacked power, and compliance with BC sampling guidelines was not evaluated.…”

Section: Blood Sample Antisepsismentioning

confidence: 97%

Contaminants in blood cultures: importance, implications, interpretation and prevention

Dargère

Cormier

Verdon

2018

Clinical Microbiology and Infection

133

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Each institution should have an efficient policy to prevent BCC, emphasizing the importance of following guidelines for prescribing and collecting BCs. Training healthcare workers should focus on detrimental influence on patient care and highlight the work and costs due to contaminants. The accurate differentiation of a contaminant from a true pathogen relies on a multidisciplinary approach and the clinical judgement of experienced practitioners.

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Section: Blood Sample Antisepsismentioning

confidence: 97%

Contaminants in blood cultures: importance, implications, interpretation and prevention

Dargère

Cormier

Verdon

2018

Clinical Microbiology and Infection

133

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“…Os autores evidenciaram que as taxas de contaminação do sangue não foram diferentes quando o álcool isopropílico e a clorexidina foram comparados. 11 Uma revisão 12 das diretrizes americanas, inglesas e francesas constatou que não existe um consenso quanto à forma de aplicação dos antissépticos. Enquanto as diretrizes americana e inglesa não são claras quanto à limpeza da pele antes de aplicar o antisséptico (uma abordagem que pode melhorar a sua eficácia, reduzindo a quantidade de bactérias e material proteico sobre a pele), as diretrizes francesas recomendam limpar a pele com um detergente antes da desinfecção.…”

Section: Discussionunclassified

Técnicas de antissepsia em procedimentos cirúrgicos ortopédicos: Um estudo comparativo

Mendes

Carvalho

et al. 2020

Rev Bras Ortop

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Resumo Objetivo Comparar as técnicas de antissepsia utilizando clorexidina degermante associada a álcool etílico e a clorexidina alcoólica versus clorexidina degermante associada a clorexidina alcoólica, em procedimentos cirúrgicos ortopédicos. Métodos Trata-se de um estudo clínico, primário, randomizado, analítico e de centro único, constituído por 170 pacientes ortopédicos submetidos a abordagem cirúrgica, alocados em 2 grupos aleatórios, nos quais foram testados clorexidina degermante + clorexidina alcoólica (grupo CDCA) e clorexidina degermante + álcool etílico a 70% + clorexidina alcoólica (grupo CDACA). Foram realizadas culturas nos meios manitol e eosina azul de metileno (EAM) de amostras colhidas nos períodos de pré-degermação (0), pós-degermação (1) e após a incisão suturada (2). Resultados Em relação ao crescimento bacteriano nos meios de cultura manitol e EAM entre os grupos, em cada período de estudo (0, 1 e 2), não ocorreu diferença estatística significativa nesta pesquisa. Na avaliação do tipo de crescimento bacteriano nos meios de cultura manitol e EAM, também não foi constatada significância estatística entre os grupos. Conclusão Não ocorreu diferença entre as técnicas utilizadas na antissepsia para prevenção de infecção de sítio cirúrgico em procedimentos ortopédicos, mas, ao final do trabalho, foi possível a elaboração de um protocolo de medidas para realização de prevenção infecciosa nesses procedimentos.

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“… 17 No significant difference exists among contemporary antiseptics (chlorhexidine solutions, isopropyl alcohol, tincture of iodine, and povidone-iodine) regarding their ability to reduce BCC, leaving these topical applications at an impasse in their efficacy. 18 , 19 , 20 , 21 Their ability to eliminate contaminants is chiefly undermined by out-of-reach subsurface skin flora. While blood culture sample acquisition via venipuncture is encouraged over the use of existing intravenous lines due to the risk of these lines harboring contaminants in large quantities, 22 , 23 piercing the skin to draw blood will confine organic debris within the needle lumen.…”

Section: Introductionmentioning

confidence: 99%

Initial Specimen Diversion Device Utilization Mitigates Blood Culture Contamination Across Regional Community Hospital and Acute Care Facility

Povroznik¹

2022

American Journal of Medical Quality

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A West Virginia regional community hospital incorporated an initial specimen diversion device (ISDD) into conventional blood culture protocol with the objective to bring the hospital-wide blood culture contamination (BCC) rate from a 3.06% preintervention rate to a target performance level below 1%. Emergency department staff, laboratory phlebotomists, and nursing staff on acute-critical care floors were trained on ISDD (Steripath Gen2, Magnolia Medical Technologies, Inc., Seattle, WA) operating procedure and utilized the device for blood culture sample collection with adult patients from September 2020 through April 2021. Of 5642 blood culture sets collected hospital-wide, 4631 were collected with the ISDD, whereas the remaining sets were collected via the conventional method. The ISDD BCC rate of 0.78% differed from the conventional method BCC rate of 4.06% observed during the intervention period (chi-squared test P < 0.00001). The ISDD group attained a sub-1% BCC rate to satisfy the intervention objective.

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Isopropyl alcohol is as efficient as chlorhexidine to prevent contamination of blood cultures

Cited by 14 publications

References 14 publications

Contaminants in blood cultures: importance, implications, interpretation and prevention

Contaminants in blood cultures: importance, implications, interpretation and prevention

Técnicas de antissepsia em procedimentos cirúrgicos ortopédicos: Um estudo comparativo

Initial Specimen Diversion Device Utilization Mitigates Blood Culture Contamination Across Regional Community Hospital and Acute Care Facility

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