Isolation Studies From Stem Extract of Pistacia Integerrima Stew. Ex Brand

Bibi, Yamin; Qayyum, Abdul; Nisa, Sobia; Waheed, Abdul; Chaudhary, Muhammad Fayyaz

doi:10.4067/s0717-97072016000200014

Cited by 6 publications

(9 citation statements)

References 12 publications

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“…As more people become aware of the potency and the adverse effects of synthetic drugs, there is a growing interest in natural drugs with various chemical structures and bioactivity against many diseases (Boer, Lamxay, & Björk, ). The chemically diverse compounds in medicinal plants, in which complex structures have therapeutic potential, are hard to synthesize in the laboratory (Bibi, Qayyum, Nisa, Waheed, & Chaudhary, ).…”

Section: Introductionmentioning

confidence: 99%

Use of spinning band distillation equipment for fractionation of volatile compounds ofCopaiferaoleoresins for developing a validated gas chromatographic method and evaluating antimicrobial activity

Ribeiro

Arruda

Silva

et al. 2018

Biomedical Chromatography

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Copaifera is a tree that produces an oleoresin that has great historical and economic importance. These oleoresins display several pharmacological properties, such as antiinflammatory and antimicrobial, among others. The commercialization of Copaifera oleoresin occurs, in many cases, without any quality control, which facilitates its adulteration. Validated analytical methods can provide a safe quality control. In this work, the 800 Automatic Spinning Band Distillation equipment was used to perform the fractionation of the volatile oils obtained by hydrodistillation of Copaifera multijuga, C. paupera, C. Publifora and C. langsdorffii, aiming to isolate and purify the major compounds present in these oils. For purification, classical column chromatography was used, furnishing six isolated sesquiterpenes. The sesquiterpenes were used as standards in the development and validation of the method by GC-FID. The evaluated parameters were selectivity, linearity, precision, accuracy and robustness and they are all in accordance with ANVISA and International Conference on Harmonization guidelines. The developed method is reliable for the quantification of sesquiterpenes in Copaifera oleoresins. Both volatile oils and isolated sesquiterpenes had their minimum inhibitory concentration determined against strains of Gram-negative and Grampositive bacteria and yeasts. Copaifera langsdorffi oleoresin was the only one active against all of the evaluated microorganisms, displaying good antimicrobial potential.

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Section: Introductionmentioning

confidence: 99%

Use of spinning band distillation equipment for fractionation of volatile compounds ofCopaiferaoleoresins for developing a validated gas chromatographic method and evaluating antimicrobial activity

Ribeiro

Arruda

Silva

et al. 2018

Biomedical Chromatography

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“…It contains 60% tannin and 1.2% volatile oil. It contains tetracyclic triterpenes, resin, pistacieonic acids A and B, essential oils, camphene, caprylic acids, cineol, α-pinene and others 20 . Leaves and bark are rich in tannin.…”

Section: Chemical Constituentsmentioning

confidence: 99%

“…Seeds contain amino acids, triterpenoids, proteins, sterols, and dihydromalvic acid 5 . The galls contain pistagremic acid, which acts as a natural terpene inhibitor of βsecretase 7,20 . The leaves contain carotenoids, triterpenoids, flavonoids, and catechins.…”

Section: Chemical Constituentsmentioning

confidence: 99%

Untitled

2023

IJPSR

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Karkatshringi (Pistacia integerrima) is an essential Ayurvedic medicinal plant belonging to the family Anacardiaceae. The plant originated in India and grows in the ranges of the north-western Himalayas. It is distributed over China, Afghanistan, Pakistan, and Nepal. The flowers of this plant is small and red, fruits are shiny and brown. Galls are hollow, horn-shaped, bitter and used for medicinal purposes. Gall powder is most commonly used in diseases such as cough, diarrhoea, fever, etc. also effective against staphylococci, pseudomonas and Escherichia coli bacteria. The different parts of the plant contain amino acids, sterols, alkaloids, flavonoids, tannins and saponin. In Pistacia integerrima, the volatile chemical constituents are extracted by hydro distillation or liquid-liquid extraction. Pistacia integerrimais associated with fungi which causes rust and blight diseases. Traditionally it is used for rheumatic pain, analgesic, and antipyretic effects. Karkatshringi is an important ingredient of Ayurvedic formulations like Chavyanprash, Dashmularista and Shringyadi Churna. Galls are used in the treatment of diarrhoea. Diabetic patients also use it. Essential oil of Pistacia integerrima was used for in-vitro studies like antioxidant activity, angiogenesis, and mast cell degranulation. Karkatshringi studied for its various activities such as anti-inflammatory, anti-oxidant, antibacterial, anti-cancer, anti-diarrhoeal, anti-convulsant, muscle relaxant, etc. This article includes detail information of Pistacia integerrima related to chemical constituents and pharmacological activities. INTRODUCTION:As per Ayurveda, karkatshringi is the most important medicinal plant. The galls of Pistacia integerrima are typically used in the treatment of paediatric disease. According to Acharya Charaka, the plant consists of the Hikkanigrahan and Kasaharagana, which are explained in vatajKasa and Kapha 1 . As a moderate-sized, broadleaf tree, the karkatshringi can be found in Nepal, China, Afghanistan, Pakistan and the northwest& West Himalayas ranges 2 .

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“…Three fractions were drawn up through liquid-liquid extraction with n-hexane, chloroform, and ethyl acetate solvents. Doses of 100 and 300 mg/mL from the ethanolic extract and 30 and 100 mg/mL from the fractions (n-hexane, chloroform, and ethyl acetate) were prepared following steps (Figure 2) (16).…”

Section: Preparation Of Ethanolic Extract and Fractionsmentioning

confidence: 99%

High-performance thin-layer chromatography fingerprinting and anti-inflammatory and antinociceptive activities of Pyracantha coccinea M.Roem.: A laboratory-based study

Taheri

Naderi

Ayatollahi

et al. 2021

Cell Mol Biol (Noisy-le-grand)

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This study aimed to investigate the high-performance thin-layer chromatography (HPTLC) fingerprinting and in-vivo anti-inflammatory and antinociceptive activities of different leaf extracts (ethanolic extract, n-hexane, chloroform, and ethyl acetate) of Pyracantha coccinea M.Roem. plant. A total of one hundred and twenty-four Wistar rats for anti-inflammatory and antinociceptive tests (carrageenan and formalin tests, respectively) were treated with two doses of the ethanolic extract (100 and 300 mg/kg), two doses of other plant fractions (30 and 100 mg/kg), Diclofenac (25 mg/kg) as the positive control, and normal saline as the negative control group, by oral gavage route. HPTLC fingerprinting is used for assay of terpenoids, flavonoids, alkaloids, and antioxidant activity. Treatment of the animal with the ethanolic extract at doses of 100 and 300 mg/kg, both ethyl acetate and chloroform fractions at the dose of 30 mg/kg and 100 mg/kg decreased the pain score in the formalin test and paw edema caused by carrageenan relative to control group significantly. Moreover, these extracts reported the highest amounts of flavonoid contents. In conclusion, phytochemicals present in Pyracantha coccinea M.Roem. leaves have anti-inflammatory and antinociceptive activities. Future studies are needed to identify the compounds with the anti-inflammatory and antinociceptive potential present in the plant.

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Isolation Studies From Stem Extract of Pistacia Integerrima Stew. Ex Brand

Cited by 6 publications

References 12 publications

Use of spinning band distillation equipment for fractionation of volatile compounds ofCopaiferaoleoresins for developing a validated gas chromatographic method and evaluating antimicrobial activity

Use of spinning band distillation equipment for fractionation of volatile compounds ofCopaiferaoleoresins for developing a validated gas chromatographic method and evaluating antimicrobial activity

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High-performance thin-layer chromatography fingerprinting and anti-inflammatory and antinociceptive activities of Pyracantha coccinea M.Roem.: A laboratory-based study

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