“…Kashmir or Indian Saffron is traditionally used in India as antispasmodic and aphrodisiac, treating dermal diseases, kidney–urinary disorders, and rheumatoid arthritis with widespread cosmetics usage as per folklore, Ayurveda, Siddha, Sowa Rigpa, and Unani medicinal systems [ 1 , 22 , 23 , 24 , 25 , 26 , 27 ]. The recent scientific studies on KCS have shown its potential in AD, cardiac functions, immunomodulatory activity, and anti-tumor agents [ 3 , 28 , 29 , 30 , 31 , 32 , 33 , 34 ]. This increased valuation and consistent growth in the KCS consumption in health benefits have prompted the demand and interest in research as a dietary supplement and nutraceutical.…”