Isolation, purification, and characterization of novel polysaccharides from lotus (Nelumbo nucifera) leaves and their immunostimulatory effects

Song, Young-Ran; Han, Ahram; Lim, Tae‐Gyu; Lee, Eunjung; Hong, Hee‐Do

doi:10.1016/j.ijbiomac.2019.01.131

Cited by 48 publications

(55 citation statements)

References 45 publications

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“…The phenomenon might be the reason that the higher temperature could lead to faster and easier mass transfer of water‐soluble CPs from the cell wall into the extract and enhance the solubility of CPs in the extracting solvent. Nevertheless, the exorbitant temperature can bring about degradation of some thermo‐sensitive matters in the CPs [10] . Therefore, the optimum extraction temperature 60 °C was accepted in the work.…”

Section: Resultsmentioning

confidence: 99%

“…Nevertheless, the exorbitant temperature can bring about degradation of some thermo-sensitive matters in the CPs. [10] Therefore, the optimum extraction temperature 60°C was accepted in the work. The results agree with the previous research on the extraction of other polysaccharides.…”

Section: Effect Of Extraction Temperature On the Yield Of Cpsmentioning

confidence: 99%

“…The CHMs hawthorn, lotus leaf, Fagopyrum tataricum , semen cassiae, Lycium barbarum and Poria cocos are the materials for both food and medicine called ‘medicine food homology’ in China [3] . Numerous studies focused on the characteristics and bioactivities of single polysaccharide from one of the above CHMs, which were shown in Table 1 [4–23] . However, to the best of our knowledge, there is no information about the structural characterization of compound polysaccharides (CPs) from the above CHMs and their antioxidant activities to date.…”

Section: Introductionmentioning

confidence: 99%

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A Novel Optimization of Water‐Soluble Compound Polysaccharides from Chinese Herbal Medicines by Quantitative Theory and Study on Its Characterization and Antioxidant Activities

Yang

Feng

et al. 2020

Chemistry & Biodiversity

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The present study optimized the extraction characterization and antioxidant activities of water-soluble compound polysaccharides (CPs) from hawthorn, lotus leaf, Fagopyrum tataricum, semen cassiae, Lycium barbarum, and Poria cocos Chinese herbal medicines that have mass ratios of 4 : 2 : 2 : 1.5 : 1 : 1. The CPs yield equation was predicted using quantitative theory, to which a maximum CPs yield of 7.18 � 0.24 % under the following optimal extraction conditions: a water-to-raw material ratio of 30 mL/g, an extraction temperature of 65°C, an extraction time of 45 min, and extraction mode ultrasonic-assistant extraction. CPs were consisted of

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Section: Resultsmentioning

confidence: 99%

Section: Effect Of Extraction Temperature On the Yield Of Cpsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

A Novel Optimization of Water‐Soluble Compound Polysaccharides from Chinese Herbal Medicines by Quantitative Theory and Study on Its Characterization and Antioxidant Activities

Yang

Feng

et al. 2020

Chemistry & Biodiversity

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“…Among them flavonoids have attracted much attention recently due to their significant antioxidant activity. Some extraction techniques were used to extract flavonoids from dry leaves such as the water decocting method [21], enzyme-assisted extraction [22], etc. However, the extraction solvent is difficult to infiltrate into the medicinal materials and the medicinal components are difficult to dissolve and diffuse out of the material cells.…”

Section: Introductionmentioning

confidence: 99%

A Novel Green Extraction Technique for Extracting Flavonoids from Folium nelumbinis by Changing Osmosis Pressure

et al. 2020

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A new green and sustainable extraction technique, namely osmosis extraction (OE), was developed for efficient extracting flavonoids from Folium nelumbinis by changing the osmotic pressure. The antioxidant activities of the extracted flavonoids were also evaluated. Ethanol and ammonium sulfate were selected for the OE system because they are environmentally friendly. The maximum flavonoids concentration in the top phase was obtained with an ethanol volume fraction of 42.0% and the salt mass of 1.9 g. The kinetic behavior of the extraction process showed that OE had higher efficiencies especially coupled with ultrasonication due to the accompanying and serious morphological changes of Folium nelumbinis cells observed by digital microscope and nano-computed tomography (nano-CT). Results of morphological and anatomical features showed that the higher intracellular chemical potential made the cell expand and even led to bursting. The results also showed that the extraction efficiency of flavonoids with high antioxidant activities was higher than that of the traditional method. The interface effect enhanced the extraction during the salting-out extraction and osmosis was the main factor that improved the extraction efficiency.

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“…There is much research concerned with lotus leaves and seeds [4,5,6,7]. It has been reported that the extract from lotus leaves and seeds have multiple bioactivities, such as being anti-oxidant [8,9], anti-inflammatory [10], immuno-modulatory [11], and anti-obesity [12] etc. The bioactivities of lotus are due to the functional components in lotus including polysaccharides, polyphenols, flavonoids etc.…”

Section: Introductionmentioning

confidence: 99%

Separation, Identification, and Antioxidant Activity of Polyphenols from Lotus Seed Epicarp

Huang

Feng

et al. 2019

Molecules

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Lotus seed epicarp, the main by-product of lotus seed processing, is abundant in polyphenols. In this study, polyphenols in lotus seed epicarp were separated by Sephadex LH-20 gel filtration chromatography to yield Fraction-I (F-I), Fraction-II (F-II), and Fraction-III (F-III). The polyphenol compounds in the three fractions were identified by UPLC-MI-TOF-MS. Six kinds of polyphenol compounds including cyanidin-3-O-glucoside, procyanidin trimer, and phlorizin were identified in F-I, and prodelphinidin dimer B, procyanidin dimer, and quercetin hexoside isomer were found in F-II. However, there was only procyanidin dimer identified in F-III. The in vitro antioxidant activities of the three fractions were also investigated. We found F-I, F-II, and F-III had strong potential antioxidant activities in the order of F-III > F-II > F-I. Our results suggested that polyphenols from lotus seed epicarp might be suitable for use as a potential food additive.

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Isolation, purification, and characterization of novel polysaccharides from lotus (Nelumbo nucifera) leaves and their immunostimulatory effects

Cited by 48 publications

References 45 publications

A Novel Optimization of Water‐Soluble Compound Polysaccharides from Chinese Herbal Medicines by Quantitative Theory and Study on Its Characterization and Antioxidant Activities

A Novel Optimization of Water‐Soluble Compound Polysaccharides from Chinese Herbal Medicines by Quantitative Theory and Study on Its Characterization and Antioxidant Activities

A Novel Green Extraction Technique for Extracting Flavonoids from Folium nelumbinis by Changing Osmosis Pressure

Separation, Identification, and Antioxidant Activity of Polyphenols from Lotus Seed Epicarp

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