Isolation of Zika Virus from Febrile Patient, Indonesia

Perkasa, Aditya; Yudhaputri, Frilasita A.; Haryanto, Sotianingsih; Hayati, Rahma; Ma’roef, Chairin Nisa; Antonjaya, Ungke; Yohan, Benediktus; Myint, Khin Saw Aye; Ledermann, Jeremy P.; Rosenberg, Ronald; Powers, Ann M.; Sasmono, R. Tedjo

doi:10.3201/eid2205.151915

Cited by 74 publications

(63 citation statements)

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“…2010 yılında Kamboçya'da, 2012 yılında Filipinler'de, 2013 yılında Tayland'da, 2014 yılında Endonezya'da Zika virüs olguları tespit edildi (54)(55)(56)(57) . Yapılan filogenetik çalışmaların sonucu, Tayland'da tespit edilen virüsün Kamboçya ve Fransız Polinezyası'nda ki virüs ile yüksek oranda homoloji gösterdiği şeklinde idi (58) .…”

Section: Günümüzde Zika Virusunclassified

Zika Virus

Şahin¹,

Mihmanlı²

2016

Okmeydani Medical Journal

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Section: Günümüzde Zika Virusunclassified

Zika Virus

Şahin¹,

Mihmanlı²

2016

Okmeydani Medical Journal

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“…The ZIKV re-emerged in 2007 in Yap Island in the Federated States of Micronesia and now has a widespread distribution in Southeast Asia, Polynesia, and the Americas. ZIKV was known to be circulating in the Indonesian archipelago for decades (Olson and Ksiazek, 1981; Olson et al, 1983); however it was successfully isolated and characterized to be of the Asian lineage only recently (Perkasa et al, 2016). …”

Section: Introductionmentioning

confidence: 99%

Genomic characterization of Zika virus isolated from Indonesia

et al. 2017

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Zika virus (ZIKV) JMB-185 strain was isolated from a febrile patient in Jambi, Indonesia in 2014. To understand its genetic characteristics, we performed whole genome sequencing using the Ion Torrent PGM platform on the supernatant of the first passage. The phylogenetic analysis showed that the isolate was not closely related to the Brazilian ZIKV associated with microcephaly or isolates from the recent Singapore Zika outbreak. Molecular evolution analysis indicated that JMB-185 strain may have been circulating in the Southeast Asia region, including Indonesia since 2000. We observed high nucleotide sequence identity between Indonesia, Thailand, Singapore, and American strains although unique amino acid substitutions were also observed. This report provides information on the genomic characteristics of Indonesian ZIKV which may be used for further studies.

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“…During the research on new strains of Zika virus isolated from A. africanus collected in Zika forest, one of the researchers became ill with maculopapular rash on the face, neck, trunk, and upper arms, slight malaise with pain in the back and febrile response and Zika virus could be isolated from a serum sample while he was febrile (Simpson 1964). Subsequently, virus isolation has been made from different countries including Nigeria (Moore et al 1975;Fagbami 1979), Ivory Coast in 1999(Akoua-Koffi et al 2001, Cambodia , Thailand (Buathong et al 2015), the Philippines (Alera et al 2015), Indonesia (Perkasa et al 2016), and Brazil Calvet, Aguiar, et al 2016).…”

Section: Epidemiology Transmission and Spreadmentioning

confidence: 99%

Zika virus – emergence, evolution, pathology, diagnosis, and control: current global scenario and future perspectives – a comprehensive review

Singh

Dhama

Malik

et al. 2016

Veterinary Quarterly

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This review converses the Zika virus which has attained global concern due to its rapid pandemic potential and impact on humans. Though Zika virus was first isolated in 1947, till the recent large-scale outbreak which occurred in Micronesia, in 2007, the virus was placed into the innocuous pathogen category. The World Health Organization on 1 February 2016 declared it as a 'Public Health Emergency of International Concern.' Of the note, American as well as Pacific Island strains/isolates is relatively closer to Asian lineage strains. The African and American strains share more than 87.5% and 95% homologies with Asian strains/isolates, respectively. Asian strains form independent clusters, except those isolated from China, suggesting relatively more diversity than African strains. Prevention and control are mainly aimed at the vector population (mosquitoes) with Aedes aegypti being the main species. Surveys in Africa and Asia indicated seropositivity in various animal species. However, so far its natural reservoir is unknown. There is an urgent need to understand why Zika virus has shifted from being a virus that caused mild illness to unforeseen birth defects as well as autoimmune-neurological problems. Unfortunately, an effective vaccine is not available yet. Availability of cryo-electron microscopy based on 3.8 A resolution revealing mature Zika virus structure and the probable virus attachment site to host cell would provide critical insights into the development of antiviral treatments and vaccines.

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Isolation of Zika Virus from Febrile Patient, Indonesia

Cited by 74 publications

References 10 publications

Zika Virus

Zika Virus

Genomic characterization of Zika virus isolated from Indonesia

Zika virus – emergence, evolution, pathology, diagnosis, and control: current global scenario and future perspectives – a comprehensive review

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