Isolation of Properdin From Human Plasma.

Isolation of Partially Purified Properdin from Bovine Serum by Cold Ethanol Fractionation.

“…Observations that the serum of patients with rheumatoid arthritis agglutinated sensitized bacteria, red cells, and other particles (4,5,6), have led to development of the sensitized sheep cell agglutination (SSCA) reaction as a phenomenon occurring most frequently in rheumatoid arthritis ( 7,8,9,10). Although this microorganism is considered of low virulence or a commensal for rats (2,3), this strain isolated in our laboratory has shown a specific affinity for joints, bone, and periarticular tissues after intravenous injection.…”