Isolation of Treponema and Tannerella spp. from equine odontoclastic tooth resorption and hypercementosis related periodontal disease

Abstract

This is the first report in which known and novel Treponema and Tannerella spp. were isolated in association with EOTRH-related periodontal disease.

Radiological prevalence of equine odontoclastic tooth resorption and hypercementosis

“…No apparent breed predisposition has been documented yet, even though in most studies Thoroughbreds and Warmbloods were over represented [3,[6][7][8]28]. In the present study, there was no significant breed predilection either.…”

Influence of dental materials on cells of the equine periodontium

“…In contrast with the increased IL-1b expression observed in LPS-stimulated human periodontal ligament cells (without selection of the fibroblasts) [35], increased expression of COX-2 and TNF-a [23] or of IL-6 and TNF-a [34] has been detected in human gingival fibroblasts. Porphyromonas gingivalis belonging to the group of red complex bacteria, are not only found in humans [37] but also in periodontitis-affected horses [38]. Our main finding was a high expression of IL-6 after 2 h of incubation with LPS, indicating an effect of LPS, although this effect was not comparable to the findings with the dental materials.…”

Equine odontoclastic tooth resorption and hypercementosis affecting all cheek teeth in two horses: Clinical and histopathological findings

“…; Earley and Rawlinson ; Sykora et al . ). Clinically, most cases present with varying degrees of gingivitis, periodontitis, gingival recession, alveolar bone protrusion and periapical abscessation with associated drainage tracts (Staszyk et al .…”

“…The aetiology of this condition is currently poorly understood but recent work by Sykora et al . () has revealed a potential involvement of Treponema and Tannerella spp. in the pathogenesis of periodontal disease that can occur with EOTRH.…”