Isolation of <i>Pasteurella septica</i> from a lion‐bite wound and lion's mouth

McGeachie, J.

doi:10.1002/path.1700750228

Cited by 23 publications

(8 citation statements)

References 6 publications

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“…Similar to that for bites from their smaller domestic relatives, Pasteurella infection is a high risk for bites from large cats, including lions, tigers, cougars, and others (159,162,164,166,293,(371)(372)(373)(374)(375). Cases of Pasteurella infections have also been reported for bites or exposure to mucous secretions from other wild and domestic animals, including rats, opossums, horses, and rabbits (166,259,287,295,376).…”

Section: Rare Cases Of Zoonotic Transmission Through Wild Animalsmentioning

confidence: 99%

Pasteurella multocida: from Zoonosis to Cellular Microbiology

2013

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SUMMARY In a world where most emerging and reemerging infectious diseases are zoonotic in nature and our contacts with both domestic and wild animals abound, there is growing awareness of the potential for human acquisition of animal diseases. Like other Pasteurellaceae , Pasteurella species are highly prevalent among animal populations, where they are often found as part of the normal microbiota of the oral, nasopharyngeal, and upper respiratory tracts. Many Pasteurella species are opportunistic pathogens that can cause endemic disease and are associated increasingly with epizootic outbreaks. Zoonotic transmission to humans usually occurs through animal bites or contact with nasal secretions, with P. multocida being the most prevalent isolate observed in human infections. Here we review recent comparative genomics and molecular pathogenesis studies that have advanced our understanding of the multiple virulence mechanisms employed by Pasteurella species to establish acute and chronic infections. We also summarize efforts being explored to enhance our ability to rapidly and accurately identify and distinguish among clinical isolates and to control pasteurellosis by improved development of new vaccines and treatment regimens.

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Section: Rare Cases Of Zoonotic Transmission Through Wild Animalsmentioning

confidence: 99%

Pasteurella multocida: from Zoonosis to Cellular Microbiology

2013

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“…A better description of the organism would be of value; it is of considerable veterinary importance and under certain circumstances may also be a human pathogen (Cawson & Talbot, 1955). The organism is a normal inhabitant of the nose and throat of dog and cat (Smith, 1955); dog and cat bites, and more rarely those of other animals (McGeachie, 1958) form one group of the human infections. The other group is made up of 'internal' infections, that is, infections not involving direct inoculation as with a bite; the majority of these are associated with the upper respiratory tract.…”

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confidence: 99%

A Taxonomic Study of Pasteurella septica, especially of Strains Isolated from Human Sources

Talbot

Sneath

1960

Journal of General Microbiology

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SUMMARY:The characteristics of fifty-nine strains of Pasteurella septica, mostly derived from human lesions, were analysed by an electronic computer. The cat strains showed a high degree of similarity to each other, while the dog strains were more variable. Most human infections other than those due to bites seem to be due to strains which probably originated from cats. The analysis suggests that P. septica is distantly related to P . pestis and P . pseudotuberculosis but that the two latter are closely related to each other.Most text-books of systematic bacteriology include in the genus Pasteurella the three organisms Pmteurella septica, P. pestis and P. pseudotzlberclulosis and sometimes also the causative organism of tularaemia. They usually give the haemorrhagic septicaemia bacterium as the type species of the group. Topley and WiZsm's Principles (1955) pointed out that it is very doubtful whether the recognition of several distinct species is justified. There are no consistent biochemical or serological differences detectable by ordinary methods between strains of P. septica isolated from different animals; to all appearances these strains are identical. A better description of the organism would be of value; it is of considerable veterinary importance and under certain circumstances may also be a human pathogen (Cawson & Talbot, 1955). The organism is a normal inhabitant of the nose and throat of dog and cat (Smith, 1955); dog and cat bites, and more rarely those of other animals (McGeachie, 1958) form one group of the human infections. The other group is made up of 'internal' infections, that is, infections not involving direct inoculation as with a bite; the majority of these are associated with the upper respiratory tract.Systematic analysis of a large number of strains of the species by orthodox methods is not a satisfactory procedure because the similarity must necessarily be close and personal bias is likely to influence the result. The principles of classification described by Sneath (1957a, b) are based on the assumption that each feature of an organism has equal taxonomic significance. A large number of characteristics of a large number of strains can be compared easily by a mechanical device, such as an electronic computer, and the degree of * Present address : Department of Pathology, Kingston Hospital, Kingaton-on-Thames, surrey.

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Section: Discussionmentioning

confidence: 99%

“…Human skin flora, including Staphylococcus aureus and Streptococcus viridans, must be covered, and consideration also given to possible contamination by environmental organisms such as Clostridium tetani, introduced at the time of the trauma. 60,66,69,[73][74][75][76][77][78][79][80] Because polymicrobial infections have been reported, treatment with a broad-spectrum antibiotics such as a beta-lactam/beta-lactamase inhibitor combination is considered standard of care for all large cat bites. For patients who are penicillin allergic, data from the 1999 Emergency Medicine Animal Bite Infection Study Group would indicate that a second-generation cephalosporin with anaerobic activity or a combination of a fluoroquinolone and clindamycin may be utilized.…”

Section: Management Of Large Felid Attacksmentioning

confidence: 99%

Human Attacks by Large Felid Carnivores in Captivity and in the Wild

Shepherd

Mills

Shoff

2014

Wilderness & Environmental Medicine

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Whereas those who live in the native ranges of the large feline carnivores are well aware of the risks of cat and human encounters, North Americans and Europeans are increasingly exposed to exotic animals through travel, ecotourism, leisure pursuits in rural areas, occupational exposure, zoo and animal park visits, wild habitat encroachment at the urban-wildlands interface, and contact with exotic pets. In encounters during which persons have been severely injured, lapses in animal management protocols, lack of appropriate adult supervision, and intoxication have been reported. Unlike common domestic pets that have lived in close association with humans for thousands of years, no matter where individual large felines may have been raised, they remain wild carnivores with strong prey-drive and territorial instincts. The emergency management of large felid attacks is similar to that of other major trauma: stabilization; management of significant orthopedic, neurologic, vascular, and soft tissue injuries; antibiotic coverage provided for the number of organisms that inhabit their mouths and the potential for tetanus and rabies; and early management in survivors of likely posttraumatic stress disorder. We must actively explore responsible measures globally that can be taken to ensure biologically appropriate, ethical, safe, and sustainable conservation of these large carnivores in both their natural habitats and captivity.

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Isolation of Pasteurella septica from a lion‐bite wound and lion's mouth

Cited by 23 publications

References 6 publications

Pasteurella multocida: from Zoonosis to Cellular Microbiology

Pasteurella multocida: from Zoonosis to Cellular Microbiology

A Taxonomic Study of Pasteurella septica, especially of Strains Isolated from Human Sources

Human Attacks by Large Felid Carnivores in Captivity and in the Wild

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