Isolation of Four Novel Carotanoids as Possible Metabolites of Rugosic Acid A inRosa rugosaLeaves

Peroxy natural products

“…139 The carotanoid rugosal A 179 was isolated from damaged Rosa rugosa leaves along with rugosic acid A 180 and its methyl ester 181. 140,141 Production of 179 is concentrated in the leaf trichomes and the compound has antifeedant acitivity against tobacco cutworm larvae, suggesting a defensive role for this metabolite. 142 The absolute configuration of 179 was established by an application of the exciton chirality method to a derivative.…”

Inhibitory Effects of Novel Diarylheptanoids and Other Constituents of the Rhizomes of Curcuma singularis on the Catalytic Activity of Soluble Epoxide Hydrolase

“…singularis rhizomes, two new diarylheptanoids ( 1–2 ) and six known compounds ( 3–8 ) were isolated for the first time from the genus Curcuma . The chemical structures of the known compounds were identified as 3‐hydroxy‐4‐methoxy benzoic acid ( 3 ), rugosic acid B ( 4 ), 2,3‐butanediol ( 5a , 5b ), meso ‐2,3‐butanediol ( 6 ), furan‐2,3‐diol ( 7 ), and ethyl‐β‐D‐glucopyranoside ( 8 ) (Figure ) by comparison of their spectroscopic data with the literature data, respectively.…”