Isolation of Corynebacteria from Non-Specific Urethritis

Furness, G.; Kamat, Madhav; Kaminski, Zigmund C.; Seebode, Joseph J.

doi:10.1016/s0022-5347(17)61340-5

Cited by 15 publications

(5 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…No other anaerobes have been implicated in NGU.' [1][2][3][4][5][6][7][8][9][10][11][12][13] Since the anterior urethra is colonised by a great variety of anaerobic species, as well as aerobic bacteria, we considered it possible that the role of one of these might have been overlooked. Furthermore, anaerobic infections of the human urinary tract are well documented.…”

Section: Introductionmentioning

confidence: 99%

Anaerobes in men with urethritis

Fontaine

Taylor‐Robinson

Hanna

et al. 1982

Sexually Transmitted Infections

View full text Add to dashboard Cite

SUMMARY Sixty-four men with non-gonococcal urethritis (NGU), seven with gonococcal urethritis (GU), and 30 who had no symptoms or signs of urethritis were studied. Chlarnydia trachomatis was isolated from urethral specimens taken from 22% of the men with NGU, and 1 8/o with GU, but not from those who did not have urethritis even though 20 (67%) of them had a history of NGU, GU, or both. The chlamydial isolation rate for men having NGU for the first time was 30%7o. Ureaplasma urealyticum was isolated from 42% of the men with NGU, 43% of men with GU, and 27% of those without urethritis.In addition to aerobes anaerobes were isolated frequently from men whether or not they had urethritis, the most common being anaerobic Corynebacteria, peptococci, and micro-organisms of the Bacteroides-Fusobacteria group. There was no appreciable difference in the overall isolation of anaerobes from men with NGU (89%) or from those without disease (8007o). The rate of isolation of a Gram-negative anaerobic bacillus from men with NGU (50%) was, however, strikingly different to that from men with GU (14%) or from those without disease (13%o). Furthermore, this bacillus was recovered from 28 (56Db) of 50 men with NGU who were considered chlamydia-negative and from 19 (61 %) of 31 men who were both chlamydia-negative and ureaplasma-negative. The effect of antibiotic treatment was evaluated in a few patients only, so that although those from whom the Gram-negative bacillus was eliminated by tetracycline recovered clinically there is a need for a prospective therapeutic trial to evaluate further the importance of the bacillus.

show abstract

Section: Introductionmentioning

confidence: 99%

Anaerobes in men with urethritis

Fontaine

Taylor‐Robinson

Hanna

et al. 1982

Sexually Transmitted Infections

View full text Add to dashboard Cite

show abstract

“…Attempts to classify these organisms on the basis of biochemical characteristics have been undertaken. Smith (26) separated lipophilic diphtheroids isolated from the skin into seven taxonomic groups, while Furness et al reported (9) ten phenotypic groups for such coryneform bacteria isolated from nonspecific urethritis corresponding to five pathogenic types ("Corynebacterium genitalium") and five saprophytic types ("Corynebacterium pseudogenitalium") of the urogenital tract (8). Analysis of their cell walls revealed the presence of arabinose, galactose, diaminopimelic acid, and corynomycolic acids (7), which are characteristic of the genus Corynebacten'um.…”

mentioning

confidence: 99%

Genomic Diversity and Phylogenetic Relationships among Lipid-Requiring Diphtheroids from Humans and Characterization of Corynebacterium macginleyi sp. nov.

Riegel

Ruimy

Briel

et al. 1995

International Journal of Systematic Bacteriology

View full text Add to dashboard Cite

DNA relatedness experiments were performed with 38 clinical isolates and 13 reference strains of coryneform taxa exhibiting a lipid requirement for optimal growth. Forty-five of these strains split into five genomic groups at the species level, whereas six other strains remained unclustered. Genomospecies I1 fits Corynebacterium accolens, but the other genomospecies were not genetically related to any of the defined Corynebucterium species. Phylogenetic analyses of genes coding for small-subunit rRNA sequences revealed that two genomospecies (I and 111) and C. uccolens form a tight cluster within the robust branch that groups all Corynebacteriun species presently sequenced. Reference strains of biotypes C-1, C-2, and C-3 of "Corynebacterium pseudogenitulium" were found to fall into genomospecies I, as well as "Corynebacterium tuberculostearicum," Centers for Disease Control and Prevention (CDC) coryneform group G-1, and CDC coryneform group 6 -2 reference strains. Biochemical tests allowed differentiation between genomospecies except between genomospecies N and V and between six unclustered strains and genomospecies I. We propose a new classification for these lipid-requiring diphtheroids within the genus Corynebucterium with the delineation of some CDC coryneform group G-1 strains (genomospecies 111) as a new species for which the name Corynebacterium mucginleyi is proposed. The type strain is strain JCL-2 (CIP 104099), isolated from a human corneal ulcer.

show abstract

“…The organism, which has been considered a possible cause of non-specific urethritis in the male (Furness, Kamat, Kaminski, and Seebode, 1971), can be responsible for maternal and neonatal septicaemia (Carney, 1973) and sepsis (Platt, 1971). …”

Section: Haemophilus Vaginalismentioning

confidence: 99%

Importance of the so-called 'other' sexually-transmitted diseases.

Willcox¹

1975

Sexually Transmitted Infections

View full text Add to dashboard Cite

Isolation of Corynebacteria from Non-Specific Urethritis

Cited by 15 publications

References 4 publications

Anaerobes in men with urethritis

Anaerobes in men with urethritis

Genomic Diversity and Phylogenetic Relationships among Lipid-Requiring Diphtheroids from Humans and Characterization of Corynebacterium macginleyi sp. nov.

Importance of the so-called 'other' sexually-transmitted diseases.

Contact Info

Product

Resources

About