Isolation of a new glycoside from starfish, <i>Asterias amurensis</i> Lutken, and its stimulation activity on the proliferation of the UMR106 cell

Liu, Hongwei; Li, Jiankuan; Zhang, Dawei; Zhang, Xue; Song, Xiaohong; Xia, Ying; Wang, Nai‐Li; Yao, Xin‐Sheng; Cai, Guoping

doi:10.1080/14786410903034330

Cited by 6 publications

(3 citation statements)

References 9 publications

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“…Compound 215 was also obtained from the sea star Asterias rollestoni Bell and it was the first natural enolic glycoside . A glycoside compound 216 was isolated from the starfish Asterias amurensis Lutken …”

Section: Chemical Constituentsmentioning

confidence: 99%

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Chemical Constituents and Bioactivities of Starfishes: An Update

Xia

Miao

Xie

et al. 2020

Chemistry & Biodiversity

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Starfishes produce various structurally unique secondary metabolites with diverse biological activities. This review is an update summary of the new compounds and their bioactivities from starfish (the Asteroidea Class) with 71 references covering from January 2007 to December 2018. During this period, 216 new compounds were obtained from 36 species. The chemical constituents are mostly steroids, steroidal glycosides, and gangliosides. These components have been found to possess various bioactivities, including anticancer, anti-inflammation, etc.

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Section: Chemical Constituentsmentioning

confidence: 99%

“…Compound 78 (0.01–100 μ m ) significantly promoted the osteoblastic proliferation on UMR106 cells . Compound 216 could also promote the osteoblastic proliferation of UMR106 cells in the range of 0.01–100 μ m …”

Section: Bioactivitiesmentioning

confidence: 99%

Chemical Constituents and Bioactivities of Starfishes: An Update

Xia

Miao

Xie

et al. 2020

Chemistry & Biodiversity

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“…A new glycoside compound ( 460 ) was isolated from the starfish Asteria amurensis Lutken. The effects of compound 460 on UMR106 cell proliferation were screened by MTT assay and it (0.01–100 μM) significantly promotes osteoblastic proliferation [ 135 ].…”

Section: New Mnps From the Beibu Gulfmentioning

confidence: 99%

Marine Natural Products from the Beibu Gulf: Sources, Chemistry, and Bioactivities

et al. 2023

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Marine natural products (MNPs) play an important role in the discovery and development of new drugs. The Beibu Gulf of South China Sea harbors four representative marine ecosystems, including coral reefs, mangroves, seaweed beds, and coastal wetlands, which are rich in underexplored marine biological resources that produce a plethora of diversified MNPs. In our ongoing efforts to discover novel and biologically active MNPs from the Beibu Gulf, we provide a systematic overview of the sources, chemical structures, and bioactive properties of a total of 477 new MNPs derived from the Beibu Gulf, citing 133 references and covering the literature from the first report in November 2003 up to September 2022. These reviewed MNPs were structurally classified into polyketides (43%), terpenoids (40%), nitrogen-containing compounds (12%), and glucosides (5%), which mainly originated from microorganisms (52%) and macroorganisms (48%). Notably, they were predominantly found with cytotoxic, antibacterial, and anti-inflammatory activities. This review will shed light on these untapped Beibu Gulf-derived MNPs as promising lead compounds for the development of new drugs.

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