Isolation, Characterization and Structural Elucidation of Bioactive Compound in Aurora Globostellata

Abstract

Marine environment is a repository of many valuable therapeutic substances. Of the different marine biota, the benthic community, Poriferans (Sponges) are goldmine for many pharmaceutical compounds. The sponges were identified using meristic and morphometric characteristics. The sponge species which have confusion in conventional taxonomical study were subjected to 18S rRNA genomic sequencing studies. The present study of sponges, the sponge Aurora globostellata was further selected for an in-depth study based on the bioactive potential and quantum of availability. The compound was crystallized and subjected to NMR (1 H-NMR, 13 C-NMR, DEPT-135, DOSY), HR-MS, IR, UV and fluorescent analysis. The structure of the compound in this fraction was characterized and it was identified as Azasterol glycoside.