Isolation, Characterisation and Antimicrobial Activity of a Steroidal Ester from the Leaves of Cassia nigricans Vahl.

Ayo, Rachael Gbekele-Oluwa; Amupitan, J. O.; Oyewale, A. O.

doi:10.3923/rjmp.2009.69.74

Cited by 9 publications

(3 citation statements)

References 19 publications

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“…It is widely accepted that extracts having activities where MIC values are below 8 mg/ml are considered to possess some antimicrobial activity [ 16 , 130 ] and natural products with MIC values below 1 mg/ml are considered noteworthy [ 16 , 131 , 132 ]. Some publications reported antimicrobial activities of Nigerian medicinal plant extracts with MIC less than or equal to 1 mg/ml against selected organisms [ 42 , 49 , 51 , 53 , 54 , 58 , 71 , 103 , 104 , 114 , 121 , 133 , 134 - 148 ] [ Table 1 ]. Inhibitory zone diameter (IZD) is measured in millimeter (mm) when DD or AWD assays is used [ 76 , 149 , 150 ].…”

Section: Antimicrobial Investigation On Nigerian Plant Extractsmentioning

confidence: 99%

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Antimicrobial activity of Nigerian medicinal plants

Anyanwu¹,

Okoye²

2017

J Intercult Ethnopharmacol

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Antimicrobial resistance (AMR) is currently one of the major threats facing mankind. The emergence and rapid spread of multi- and pan-drug-resistant organisms (such as vancomycin-, methicillin-, extended-spectrum β-lactam-, carbapenem- and colistin-resistant organisms) has put the world in a dilemma. The health and economic burden associated with AMR on a global scale are dreadful. Available antimicrobials have been misused and are almost ineffective with some of these drugs associated with dangerous side effects in some individuals. Development of new, effective, and safe antimicrobials is one of the ways by which AMR burden can be reduced. The rate at which microorganisms develop AMR mechanisms outpaces the rate at which new antimicrobials are being developed. Medicinal plants are potential sources of new antimicrobial molecules. There is renewed interest in antimicrobial activities of phytochemicals. Nigeria boasts of a huge heritage of medicinal plants and there is avalanche of researches that have been undertaken to screen antimicrobial activities of these plants. Scientific compilation of these studies could provide useful information on the antimicrobial properties of the plants. This information can be useful in the development of new antimicrobial drugs. This paper reviews antimicrobial researches that have been undertaken on Nigerian medicinal plants.

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Section: Antimicrobial Investigation On Nigerian Plant Extractsmentioning

confidence: 99%

“…[ 49 , 92 , 111 , 112 , 143 , 165 , 169 - 173 ], Cassia spp. [ 103 , 114 , 151 , 174 - 177 ], and Allium spp. [ 57 , 102 , 104 , 178 - 180 ].…”

Section: Antimicrobial Investigation On Nigerian Plant Extractsunclassified

Antimicrobial activity of Nigerian medicinal plants

Anyanwu¹,

Okoye²

2017

J Intercult Ethnopharmacol

View full text Add to dashboard Cite

show abstract

“…The present review retrieved and compiled ethnomedicinal and ethnopharmacological information of these wound healing plants (165 species). Of the 165 species, only fifty-four (33 %) of the plants have been experimentally validated for their wound healing activities in different pharmacological, phytochemical, and toxicological studies, including [ [143] , [144] , [145] , [146] , [147] , [148] , [149] , [150] , [151] , [152] , [153] , [154] , [155] , [156] , [157] , [158] , [159] , [160] , [161] , [162] , [163] , [164] , [165] , [166] , [167] , [168] , [169] , [170] , [171] , [172] , [173] , [174] , [175] , [176] , [177] , [178] , [179] , [180] , [181] , [182] , [183] , [184] , [185] , [186] , [187] , [188] , [189] , [190] , [191] , [192] , [193] , [194] , [195] , [196] , [197] , [198] , [199] , [200] , [201] , [202] , [203] , [204] , [205] , …”

Section: Discussionmentioning

confidence: 99%