Isolation and Structure of Phytotoxic Compounds Produced by Phyllosticta sp.

Abstract

Isolation and Structure of Phytotoxic Compounds Produced by Phyllosticta sp.

Relationships between the stereochemistry and biological activity of fungal phytotoxins

“…160 Species belonging to the genus Phyllosticta are known to produce bioactive metabolites, including nonhost-specific phytotoxins, for example, phyllosinol, brefeldin, and PM-toxin. 179 Fig. 16, was assigned by combination of the application of Mosher's method [30][31][32] through the comparison of the 1 H-NMR spectra of its 11-O-SMTPA and 11-O-RMTPA esters and NOESY spectroscopy.…”

Three Oxygenated Cyclohexenone Derivatives Produced by an Endophytic Fungus

“…In contrast, (þ)-epoxydon, (þ)-desoxyepiepoxydon, (þ)-epiepoxydon and chaloxone, which have the -configuration of the epoxide group, have shown a positive Cotton effect in the same spectroscopic range. [8][9][10] To determine the absolute stereochemistry at C-4 of 1, the modified Mosher's method for the MTPA ester of 1 was carried out. MTPA esters (1a and 1b).…”

“…A number of related epoxycyclohexenone-based natural products have been reported. [5][6][7][8][9][10][12][13][14][15] Since some of these products are known to be phytotoxic, 8,9,14) we investigated whether isolated compounds 1, 2 and 3 would also exhibit phytotoxic activity. The plant growth inhibitory activities of 1, 2 and 3 were determined by seedling growth test on lettuce.…”

Antimicrobial activities of secondary metabolites produced by endophytic fungi fromSpondias mombin

“…demonstrated a non selective antibacterial activity against Gram-positive (S. aureus) and Gram-negative (E. coli) bacteria. We are not aware of any report of secondary metabolites produced by species of Guignardia with such antibiotical activity; on the other hand, several phytotoxins have been described to be produced in vitro by Phyllosticta spp., its anamorph genus (SAKAMURA et al 1969(SAKAMURA et al , 1971SAKAI et al 1970). Phomopsis has been reported to be one of the most commonly isolated endophytic genus, found within a wide range of plant hosts worldwide (UECKER 1988).…”