Isolation and molecular characterization of pathogenic Leptospira species from cattle in Zaria and its environs, Kaduna State, Nigeria

Udechukwu, Collins Chimezie; Kudi, Caleb Ayuba; Abdu, Paul Ayuba; Mamman, P. H.; Pilau, Nicholas Nathaniel; Abiayi, Elmina Abiba; Jolayemi, Kelvin Olutimilehin; Okoronkwo, Magdalene Ogbonneya; Adekola, Adewole Augustine

doi:10.1016/j.cimid.2023.102003

Cited by 2 publications

(3 citation statements)

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“…We also detected L. kirschneri , whose occurrence has been reported in Tanzania and Uganda. More surprisingly, in Benin, we detected L. interrogans DNA in two cattle, which were not found in the studies above but were predominant among the Leptospira species described in Nigeria (Udechukwu et al., 2023 ). These observations underscore the locally distribution of Leptospira species in cattle.…”

Section: Discussioncontrasting

confidence: 54%

“…Although sampling was targeted to include the tubules, which have been reported to contain the bacteria, Leptospira can be missed because it may display an aggregated distribution pattern (Yamaguchi et al., 2018 ). Additional studies suggested that Leptospira prevalence can be higher and up 32% [ n = 130] in cattle slaughterhouses from Nigeria (Udechukwu et al., 2023 ).…”

Section: Discussionmentioning

confidence: 99%

“…et al, 2018). Additional studies suggested that Leptospira prevalence can be higher and up 32% [n = 130] in cattle slaughterhouses from Nigeria (Udechukwu et al, 2023).…”

Section: Idmentioning

confidence: 99%

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Seroprevalence and renal carriage of pathogenic Leptospira in livestock in Cotonou, Benin

Her,

Crespin,

Etougbétché

et al. 2024

Veterinary Medicine & Sci

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BackgroundLeptospirosis is a zoonotic disease. It is particularly prevalent in tropical countries and has major consequences for human and animal health. In Benin, the disease's epidemiology remains poorly understood, especially in livestock, for which data are lacking.ObjectivesTo characterise Leptospira seroprevalence and locally circulating serogroups in livestock from Cotonou and to estimate the prevalence of Leptospira renal carriage in cattle.MethodsWe conducted a cross‐sectional study in February 2020 during which livestock were sampled at an abattoir and in an impoverished city district. We analysed blood samples from 279 livestock animals (i.e. cattle, sheep, goats and pigs) using the microscopic agglutination test. Additionally, samples of renal tissue from 100 cattle underwent 16s rRNA (rrs) real‐time PCR analysis.ResultsFor the 131 cattle, 85 sheep, and 50 goats tested, seroprevalence was 18% (95% confidence interval [CI] [12%, 26%]), 9% (95% CI [4%, 17%] and 2% (95% CI [0%, 9%]), respectively, and most of the seropositive animals were associated with 1:100 titres. All 13 pigs were seronegative. Leptospira DNA was found in the renal tissue of 10% (95% CI [5%, 18%]) of the cattle tested (n = 100). Leptospira borgpetersenii was the main species present (n = 7), but Leptospira interrogans (n = 2) and Leptospira kirschneri (n = 1) were also detected. Various serogroups (Canicola, Grippotyphosa, Sejroe, Icterohaemorrhagiae, Pomona, Pyrogenes, Australis and Autumnalis) were detected using microscopic agglutination test without a clear predominance of any of them.ConclusionsThese results suggest that abattoir workers and people living in close contact with livestock in poor urban areas are exposed to the risk of Leptospira infection.

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Section: Discussioncontrasting

confidence: 54%

Section: Discussionmentioning

confidence: 99%