Isolation and Characterization of Phenolic Compounds from Magnoliae Cortex Produced in China.

Secondary metabolites from the root of Lindera reflexa Hemsl

“…The 1 H-1 H COSY spectrum showed that H-3″, H-4″, H- 5″, and H-6″ were connected in sequence and that δ5.36 (H-2″) and 1.76 (H-4″) had a cross-peak with δ122.3 (C-2), which indicated that C-3″ was linked to C-2. These data suggested the compound contained a menthen moiety linked to C-3 [10]. H-3″ and H-4″ had no NOE correlations, suggesting the two protons was ipso-lateral, C-3″ and C-4″ was determined to possess a trans structure by NOESY spectrum (Fig.…”

Neuritogenesis of Herbal (+)- and (−)-Syringaresinols Separated by Chiral HPLC in PC12h and Neuro2a Cells

“…The evaporation residue (17.5 g) of the CHCl 3 fraction was chromatographed on a silica gel column by a succcssive elution with n-hexane, n-hexane-EtOAc 6) was hydrolyzed by b-glucosidase (Sigma, U.S.A.) in 0.1 M acetate buffer (pH 5.0) at 37°C overnight. The reaction mixture was extracted three times with EtOAc to afford syringaresinol (31 mg).…”

Nine phenylethanoid glycosides from Magnolia officinalis var. biloba fruits and their protective effects against free radical-induced oxidative damage

“…Modern pharmacological research showed that magnolia bark extracts have effective antibacterial2, antioxidant34, anti-inflammatory56, anti-anxiety7, anti-gastric ulcer8, antitumor9, neuroprotective10, and cardiovascular protection11 activities. The bioactive components of magnolia bark extracts include mainly neolignans, lignans, sesquiterpenes, alkaloids, and phenylethanoid glycosides1213141516. Recently, magnolia bark extracts have been recognized as a food additive worldwide.…”