Isolation and characterization of luffacylin, a ribosome inactivating peptide with anti-fungal activity from sponge gourd (Luffa cylindrica) seeds

Parkash, A.; Ng, Tzi Bun; Tso, Wung-Wai

doi:10.1016/s0196-9781(02)00045-1

Cited by 75 publications

(42 citation statements)

References 12 publications

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“…Examples of plant RIPs are ricin from castor bean ( Ricinus communis ) (Endo et al ., 1987), ME1+2 from Mirabilis expansa (Vivanco et al ., 1999), RIP1 from maize (Nielsen et al ., 2001), PAP‐H from pokeweed ( Phytolacca americana ) (Park et al ., 2002a), α‐ and β‐pisavins from pea ( Pisum sativum ) seeds (Lam et al ., 1998) and ebulin1, a type II RIP from Sambucus ebulus (Girbes et al ., 1993). Hispin is a 21‐kDa RIP from hairy melon seeds (Ng and Parkash, 2002), whereas luffacylin is an arginine‐ and glutamate‐rich RIP from loofah ( Luffa cylindrical ) (Parkash et al ., 2002). A 30‐kDa RIP was isolated from dehursked barley grains (Roberts and Selitrennikoff, 1986).…”

Section: Antifungal Proteinsmentioning

confidence: 99%

The role of plant defence proteins in fungal pathogenesis

Ferreira

Monteiro

Freitas

et al. 2007

Molecular Plant Pathology

236

174

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SUMMARY It is becoming increasingly evident that a plant-pathogen interaction may be compared to an open warfare, whose major weapons are proteins synthesized by both organisms. These weapons were gradually developed in what must have been a multimillion-year evolutionary game of ping-pong. The outcome of each battle results in the establishment of resistance or pathogenesis. The plethora of resistance mechanisms exhibited by plants may be grouped into constitutive and inducible, and range from morphological to structural and chemical defences. Most of these mechanisms are defensive, exhibiting a passive role, but some are highly active against pathogens, using as major targets the fungal cell wall, the plasma membrane or intracellular targets. A considerable overlap exists between pathogenesis-related (PR) proteins and antifungal proteins. However, many of the now considered 17 families of PR proteins do not present any known role as antipathogen activity, whereas among the 13 classes of antifungal proteins, most are not PR proteins. Discovery of novel antifungal proteins and peptides continues at a rapid pace. In their long coevolution with plants, phytopathogens have evolved ways to avoid or circumvent the plant defence weaponry. These include protection of fungal structures from plant defence reactions, inhibition of elicitor-induced plant defence responses and suppression of plant defences. A detailed understanding of the molecular events that take place during a plant-pathogen interaction is an essential goal for disease control in the future.

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Section: Antifungal Proteinsmentioning

confidence: 99%

The role of plant defence proteins in fungal pathogenesis

Ferreira

Monteiro

Freitas

et al. 2007

Molecular Plant Pathology

236

174

View full text Add to dashboard Cite

show abstract

“…The final purification step was C 18 reverse‐phase HPLC. We found that the optimized purification procedure in this paper could more efficiently gain the antifungal peptide of the foxtail millet seeds, but it was a little different from the purification procedure proven useful for the purification of other antifungal proteins and peptides 20–35, 44…”

Section: Discussionmentioning

confidence: 88%

“…However, the productivity of foxtail millet is limited for various reasons, one of which is its susceptibility to fungal diseases such as downy mildew and ergot, resulting in heavy losses of yield and quality. To date, several proteins with antibacterial and/or antifungal properties have been isolated and characterized from different plant species and tissues;14–40 however, there are no reports about the antifungal peptide from foxtail millet seeds. A detailed analysis of antifungal peptide that could be effective against these diseases will therefore be used as an important step towards the final objective of enhancing the defense mechanism of foxtail millet.…”

Section: Introductionmentioning

confidence: 99%

A novel antifungal peptide from foxtail millet seeds

Lü

et al. 2011

J. Sci. Food Agric.

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“…It inhibited growth in the fungi Alternaria brassicae, Cercospora personata, F. oxysporum, Mucor sp., and R. solani with the IC50 values of 33, 42, 37, 40, and 48 μM, respectively, and spore germination in A. brassis with IC50 of 12.5 μM (Zhang et al 2015). The small RIP luffacylin from L. cylindrica seeds possesses antifngal activity (Parkash et al 2002).…”

Section: Ribosome-inactivating Proteinsmentioning

confidence: 99%

“…The 21-kDa hairy melon RIP and the arginine-and glutamate-rich small RIP luffacylin from Luffa cylindrica seeds (Parkash et al 2002) manifested antifungal activity. A type 1 RIP, designated as Jc-SCRIP, was isolated from Jatropha curcas seed coats.…”

Section: Ribosome-inactivating Proteinsmentioning

confidence: 99%

Plant antifungal proteins and their applications in agriculture

Yan

Yuan

Jiang

et al. 2015

Appl Microbiol Biotechnol

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Fungi are far more complex organisms than viruses or bacteria and can develop numerous diseases in plants that cause loss of a substantial portion of the crop every year. Plants have developed various mechanisms to defend themselves against these fungi which include the production of low-molecular-weight secondary metabolites and proteins and peptides with antifungal activity. In this review, families of plant antifungal proteins (AFPs) including defensins, lectins, and several others will be summarized. Moreover, the application of AFPs in agriculture will also be analyzed.

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Isolation and characterization of luffacylin, a ribosome inactivating peptide with anti-fungal activity from sponge gourd (Luffa cylindrica) seeds

Cited by 75 publications

References 12 publications

The role of plant defence proteins in fungal pathogenesis

The role of plant defence proteins in fungal pathogenesis

A novel antifungal peptide from foxtail millet seeds

Plant antifungal proteins and their applications in agriculture

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