Isolation and Characterization of Bioactive Streptomyces From Mangrove Ecosystem of Machilipatnam, Krishna District, Andhra Pradesh

Yasmeen, Shazia; Vijayalakshmi, M.; Munaganti, Rajesh Kumar

doi:10.22159/ajpcr.2016.v9s3.14913

Cited by 4 publications

(1 citation statement)

References 9 publications

(9 reference statements)

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“…2) followed by BLAST and SeqMatch analysis was used for molecular conformation endophytic isolate [23]. The 18S rRNA sequence was submitted to the DNA Data Bank of Japan and assigned an accession number (LC062385).…”

Section: Morphological and Molecular Identification Of Fungal Isolatementioning

confidence: 99%

Optimization of process parameters for production of antimicrobial metabolites by an endophytic fungus Aspergillus sp. CPR5 isolated from Calotropis procera root.

Verma¹,

Lal²,

Debnath³

2017

Asian J Pharm Clin Res

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Objective: To study the antimicrobial activity of crude ethyl acetate extract from endophytic fungus in Calotropis procera root.Methods: Endophytic fungus was screened for production of antimicrobial metabolites. Fermentation was carried out in 500 ml Erlenmeyer flask. Disc diffusion method was used to test antimicrobial activity of crude extract using chloramphenicol sulfate and fluconazole as a positive control.Results: A total of 14 endophytic fungi were isolated (CPR1-CPR14). Among these 14 isolates, CPR5 was found to show maximum antimicrobial activity, in compare to other isolates, against Gram-positive, Gram-negative bacteria and fungi. The antimicrobial activity was tested in opposition to Escherichia coli, Pseudomonas aeroginosa, Bacillus subtilis, Staphylococcus aureus, Ralstonia solanacearum, Xanthomonas oryzae, Penicillium chrysogenum, Candida albicans, Phoma exigua, Sclerotium rolfsii, and Sclerotinia scleratiourum. Minimum inhibitory concentration of crude extract against test microorganisms was determined. Fungus was identified as Aspergillus sp. production parameters (temperature, pH, carbon source, nitrogen source, and sodium chloride concentration) were optimized. Conclusion:Crud extract produced by the isolated endophytic fungus could be an important source of broad-spectrum antimicrobial metabolites.

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Section: Morphological and Molecular Identification Of Fungal Isolatementioning

confidence: 99%

Optimization of process parameters for production of antimicrobial metabolites by an endophytic fungus Aspergillus sp. CPR5 isolated from Calotropis procera root.

Verma¹,

Lal²,

Debnath³

2017

Asian J Pharm Clin Res

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Biotechnological potential of microbial pigments from mangrove ecosystems: a review

Venil

Usha

Devi

2020

Biotechnological Utilization of Mangrove Resources

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Study of Structurally Diverse Currently Used and Recently Developed Antimycobacterial Drugs

Almehmadi

Abdulaziz

Halawi

et al. 2023

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Despite major antimicrobial therapeutic advancements, widespread use and misuse of antimicrobial drugs have increased antimicrobial drug resistance, posing a severe danger to public health. In particular, the emergence of multidrug-resistant bacteria has provided considerable difficulty in the treatment of pathogenic infections. As a result, the creation of novel drugs to treat resistant bacteria is one of the most significant disciplines of antimicrobial research today. TB therapy has recently gained a lot of attention, in addition to developing novel and efficient antibacterial drugs to battle multidrug-resistant illnesses. The use of a different class of drugs, such as well-known drugs, their derivatives, and various new heterocyclic compounds like nitroimidazoles, imidazole analogues, triazoles, imidazopyridines, quinolines, purines, as well as thioactomycin, mefloquine, deazapteridines, benzothiadiazine and other molecules such as benzoxazines, diterpenoids, tryptanthin and phenazine and toluidine analogues followed by many other classes of compounds and their effects are also discussed. As a result, current and newly found antitubercular drugs and their toxicities and mode of action have been focused.

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Isolation and Characterization of Bioactive Streptomyces From Mangrove Ecosystem of Machilipatnam, Krishna District, Andhra Pradesh

Cited by 4 publications

References 9 publications

Optimization of process parameters for production of antimicrobial metabolites by an endophytic fungus Aspergillus sp. CPR5 isolated from Calotropis procera root.

Optimization of process parameters for production of antimicrobial metabolites by an endophytic fungus Aspergillus sp. CPR5 isolated from Calotropis procera root.

Biotechnological potential of microbial pigments from mangrove ecosystems: a review

Study of Structurally Diverse Currently Used and Recently Developed Antimycobacterial Drugs

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