Isolation and characterisation of chemical compounds from the plants, Phytolacca octandra (L.), Phytolacca dodecandra (LHerit) and Balanites aegyptiaca (L.) commonly used to control schistosomiasis transmitting snails in Kenya

Kariuki, S. T.; Kariuki, Jackline; Mailu, B. M; Muchiri, Daniel R.

doi:10.5897/ajpac2018.0749

Cited by 3 publications

(2 citation statements)

References 9 publications

(15 reference statements)

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“…Another plant secondary metabolite with antiviral activity is oleanolic acid [105]. It is reported from Syzygium aromaticum [9], Ocimum basilicum, Ocimum lamiifolium, Ocimum urticifolium, and Olea europea subsp cuspidate [11], Osyris quadripartite [91], Acokanthera schimperi [78], Dregea schimperi [88], Euphorbia abyssinica [89], and Phytolacca dodecandra [93]. Oleanolic acid has a binding affinity for SARS-CoV-2 M protease and Spike (S) glycoprotein [106].…”

Section: Medicinal Plants With Antiviral Active Componentsmentioning

confidence: 99%

Candidate Anti-COVID-19 Medicinal Plants from Ethiopia: A Review of Plants Traditionally Used to Treat Viral Diseases

Tegen

Dessie

Damtie

2021

Evidence-Based Complementary and Alternative Medicine

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Background. Emerging viral infections are among the major global public health concerns. The pandemic COVID-19 is a contagious respiratory and vascular disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). There are no medicines that can treat SARS-CoV-2 except the vaccines. Therefore, searching for plant-originated therapeutics for the treatment of COVID-19 is required. Consequently, reviewing medicinal plants used to treat different viral infections is mandatory. This review article aims to review the ethnobotanical knowledge of medicinal plants traditionally used to treat different viral diseases by the Ethiopian people and suggests those plants as candidates to fight COVID-19. Methods. Articles written in English were searched from online public databases using searching terms like “Traditional Medicine,” “Ethnobotanical study,” “Active components,” “Antiviral activities,” and “Ethiopia.” Ethnobotanical data were analyzed using the Excel statistical software program. Result. From the 46 articles reviewed, a total of 111 plant species were claimed to treat viral infections. Fifty-six (50.4%) of the plant species had reported to have antiviral active components that are promising to treat COVID-19. Lycorine, gingerol shogaol, resveratrol, rhoifolin, oleanolic acid, kaempferol, rosmarinic acid, almond oil, ursolic acid, hederagenin, nigellidine, α-hederin, apigenin, nobiletin, tangeretin, chalcone, hesperidin, epigallocatechin gallate, allicin, diallyl trisulfide, ajoene, aloenin, artemisinin, glucobrassicin, curcumin, piperine, flavonoids, anthraquinone, hydroxychloroquine, and jensenone were some of them. Conclusion. The Ethiopian traditional knowledge applies a lot of medicinal plants to treat different viral infections. Reports of the chemical components of many of them confirm that they can be promising to fight COVID-19.

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Section: Medicinal Plants With Antiviral Active Componentsmentioning

confidence: 99%

Candidate Anti-COVID-19 Medicinal Plants from Ethiopia: A Review of Plants Traditionally Used to Treat Viral Diseases

Tegen

Dessie

Damtie

2021

Evidence-Based Complementary and Alternative Medicine

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“…Nowadays, research and developmental studies on low-dose compounds, biodegradable, low-cost, and less aggressive molluscicidal activity have been intensively investigated [22,23,24]. Among the botanical groups studied, specimens of the families Phytolaccaceae and Euphorbiaceae present great molluscicidal activity for the snail’s intermediate hosts [25,26]. On the one hand, P. dodecandra (L’Herit) (synonyms: P. abyssinica Hoffm., Pircunia abyssinica Moq.…”

Section: Phytochemical Molluscicides and Schistosomiasis: What We mentioning

confidence: 99%

Phytochemical Molluscicides and Schistosomiasis: What We Know and What We Still Need to Learn

Augusto

Mello-Silva

2018

Veterinary Sciences

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Worldwide schistosomiasis remains a serious public health problem with approximately 67 million people infected and 200 million at risk of infection from inhabiting or transiting endemically active regions. Africa, South America, the Caribbean, and the Middle East are the main transmission regions of Schistosoma mansoni. The fight against transmission through the use of molluscicides is not recent and has been advocated as the only activity with the possibility of interruption of transmission in small, epidemiologically active outbreaks. Euphorbia milii var. hislopii (syn. splendens) (Des Moulins, 1826) is the most promising for use in official schistosomiasis control programs according to the WHO. In this review, we show that an understanding of some how E. milii latex affects the snail vector and their parasites from a molecular level to field conditions is lacking. On the other hand, this type of treatment could also provide a rationale for the control of schistosomiasis and other parasitosis. Several publications contribute to enforcing the use of E. milii latex in endemic countries as a cheap alternative or complement to mass drug treatment with praziquantel, the only available drug to cure the patients (without preventing re-infection).

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Status Quo and Future Perspectives of Molecular and Genomic Studies on the Genus Biomphalaria—The Intermediate Snail Host of Schistosoma mansoni

Williams

Hui

2023

IJMS

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Schistosomiasis, or also generally known as bilharzia or snail fever, is a parasitic disease that is caused by trematode flatworms of the genus Schistosoma. It is considered by the World Health Organisation as the second most prevalent parasitic disease after malaria and affects more than 230 million people in over 70 countries. People are infected via a variety of activities ranging from agricultural, domestic, occupational to recreational activities, where the freshwater snails Biomphalaria release Schistosoma cercariae larvae that penetrate the skin of humans when exposed in water. Understanding the biology of the intermediate host snail Biomphalaria is thus important to reveal the potential spread of schistosomiasis. In this article, we present an overview of the latest molecular studies focused on the snail Biomphalaria, including its ecology, evolution, and immune response; and propose using genomics as a foundation to further understand and control this disease vector and thus the transmission of schistosomiasis.

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Isolation and characterisation of chemical compounds from the plants, Phytolacca octandra (L.), Phytolacca dodecandra (LHerit) and Balanites aegyptiaca (L.) commonly used to control schistosomiasis transmitting snails in Kenya

Cited by 3 publications

References 9 publications

Candidate Anti-COVID-19 Medicinal Plants from Ethiopia: A Review of Plants Traditionally Used to Treat Viral Diseases

Candidate Anti-COVID-19 Medicinal Plants from Ethiopia: A Review of Plants Traditionally Used to Treat Viral Diseases

Phytochemical Molluscicides and Schistosomiasis: What We Know and What We Still Need to Learn

Status Quo and Future Perspectives of Molecular and Genomic Studies on the Genus Biomphalaria—The Intermediate Snail Host of Schistosoma mansoni

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