Isolated Renal Mucormycosis in Children

Isolated mucormycosis in a post-pyeloplasty kidney in an immuno-competent child

“…[67] In 2004, Jianhong et al . [8] reported 3 pediatric cases with IRM without an underlying predisposing condition. Table 1 summarizes the cases of IRM in children aged 14 years and below, reported in English literature hitherto.…”

Primary renal zygomycosis due toRhizopus oryzae

“…Additionally, deferoxamine therapy [1] and prophylaxis with voriconazole was thought as the predisposing factor to zygomycosis [29]. However, no obvious underlying diseases were found in 14 of the patients with primary renal zygomycosis [8,14,18,26,27].…”

“…In the 43 described patients including this patient for whom the sex was provided in the article, the ratio of males to females was 39 to 4. The age of the patients ranged from 3 months to 77 years [25,26] but most were adults, with only 5 involving children [11,18,26]. Most of the patients had some type of underlying diseases, including ours with disseminated zygomycosis, HIV infection in which 11 of the 13 patients were also intravenous drug abusers [13,15,16,18 Á20,22,24], diabetes [6,7,9,10], steroid therapy [12,17], viral hepatitis [8,11,14], renal transplant recipients [23] and other forms of immunocompromised conditions.…”

Isolated renal mucormycosis in an immunocompetent child

“…Mucormycosis can be divided into five subtypes-rhinocerebral, pulmonary, gastrointestinal, cutaneous and disseminated. [3] In an extensive review of mucormycosis in pediatric patients by Roilides et al ., the patterns of organ involvement identified were rhinocerebral (18%), pulmonary (16%), gastrointestinal (21%) and cutaneous (27%). [4] Renal involvement occurs in 19% of adult patients with disseminated disease.…”

“…reported three immunocompetent children with IRM all of whom recovered with surgery and anti-fungal therapy. [3] Dhua et al . have reported a case of IRM following a pyeloplasty in an immunocompetent child.…”