Isolated Pulmonary Valve Endocarditis

Chowdhury, Mohammed Andaleeb; Moukarbel, George V.

doi:10.1159/000440857

Cited by 23 publications

(26 citation statements)

References 9 publications

(10 reference statements)

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“…Secondly, PVE is also very rare and typically occurs in 1.5–2% of patients hospitalized with IE (5). It is usually associated with simultaneous involvement of other valves (6), commonly in the context of an underlying structural heart disease. A total of 70 cases of isolated PVE have been reported between 1979 and 2013 (6).…”

Section: Discussionmentioning

confidence: 99%

Pneumococcal pulmonary valve endocarditis

et al. 2017

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Pulmonary valve endocarditis is a rare type of infective endocarditis (IE). Streptococcus pneumoniae is a pathogen that is uncommonly associated with IE. A 50 year-old male was referred to us after an incidental echocardiographic finding of a pulmonary valve vegetation. The patient had a recent admission for drainage of a scrotal abscess from which S. pneumoniae was isolated, complicated by hospital acquired pneumonia and pulmonary embolism. Analysis using polymerase chain reaction of the surgically resected mass revealed signs of 16S ribosomal DNA consistent with S. pneumoniae infection. This was an extremely rare case of pneumococcal pulmonary valve IE presenting entirely asymptomatically in the absence of any known risk factors.Learning points:Streptococcus pneumoniae endocarditis can present with very few symptoms or even entirely asymptomatically, as in this case.Pulmonary valve endocarditis can affect healthy patients, even in the absence of any known predisposing risk factors or pre-existing heart conditions.An echocardiogram may be considered following severe infection with sepsis by pneumococci, to screen for vegetations that could evolve silently over the following weeks.

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Section: Discussionmentioning

confidence: 99%

Pneumococcal pulmonary valve endocarditis

et al. 2017

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“…However, isolated PVE is an extremely rare event that typically occurs in less than 2% of cases (1). From 1979 to 2013, there were only 70 reported cases of PVE (2). The mean age at presentation was 44 years and the majority of patients were male.…”

Section: Discussionmentioning

confidence: 99%

“…However, cases of fungal as well as other bacterial pathogens have also been reported in the literature. TTE is the most common modality used in the diagnosis of PVE and often requires multiple views to pick up the vegetation (2). In cases where TTE is negative despite high clinical suspicion, a transesophageal echocardiogram should be performed because of its better sensitivity and specificity.…”

Section: Discussionmentioning

confidence: 99%

Isolated pulmonary valve endocarditis masquerading as community-acquired pneumonia

Nazir

Lohani

Tachamo

et al. 2016

Journal of Community Hospital Internal Medicine Perspectives

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Isolated pulmonary valve endocarditis in intravenous drug users is a rarely reported phenomenon. We present the case of a 25-year-old male with history of intravenous drug use who presented with respiratory symptoms after failing outpatient treatment for community-acquired pneumonia. Further investigations identified multiple lung lesions with early cavitation, concerning for septic pulmonary embolism on computerized tomography scan, positive blood cultures with methicillin-susceptible staphylococcus aureus, and isolated vegetation of the pulmonic valve on transthoracic echocardiography. The patient had a complete recovery after being treated medically with intravenous oxacillin for a total of 6 weeks.

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“…1,2 Isolated PV endocarditis is very rare, accounting for less than 2.0% of hospitalizations for IE, and is extremely rare in patients with structurally normal hearts. [2][3][4] It mostly affects men, 5 and its main risk factors include intravenous drug abuse, alcohol abuse, sepsis, catheter -related infection, immunosuppression, dental extraction, and bowel surgery.…”

Section: Clinical Imagementioning

confidence: 99%