Isolated Oculomotor Nerve Paresis in Anaplastic Astrocytoma With Exophytic Invasion

Tanaka, Kazuhiro; Sasayama, Takashi; Kawamura, Atsufumi; Kondoh, Takeshi; Kanomata, Naoki; Kohmura, Eiji

doi:10.2176/nmc.46.198

Cited by 8 publications

(4 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The anatomical region and the cranial nerves more often affected were the cerebellopontine angle and trigeminal and vestibulocochlear nerves, while the oculomotor nerve was involved only 2 times. In most of the cases clinical symptoms related to the cranial nerve directly involved were present; only 5 cases of high-grade temporal glioma associated to isolated third cranial nerve palsy were reported in the literature [ 11 , [25] , [26] , [27] , [28] ]. We first report a case of temporo-mesial gliosarcoma, with exophytic pattern of growth to the ambient and crural cisterns and with sleeve involvement of the ipsilateral third cranial nerve, with encasement of the anterior choroidal, posterior communicant and posterior cerebral arteries, presenting without symptoms of peripheral neuropathy.…”

Section: Discussionmentioning

confidence: 99%

Gliosarcoma with direct involvement of the oculomotor nerve: Case report and literature review

Corvino¹,

Peca²,

Corazzelli³

et al. 2022

Radiology Case Reports

View full text Add to dashboard Cite

Gliosarcoma is a rare malignant brain tumor, characterized by a biphasic tissue pattern with alternating areas displaying glial and mesenchymal differentiation. We first report a case of temporo-mesial gliosarcoma, extended to the crural and ambient cisterns, with direct involvement of the ipsilateral third cranial nerve and encasement of anterior choroidal, posterior communicant and posterior cerebral arteries, presenting without symptoms of peripheral neuropathy. A 61-year-old woman with 1-month history of intense bilateral frontal-temporal headache resistant to pharmacological therapy and paresis of the left lower midface underwent surgical resection, through pterional trans-sylvian approach, of a right temporo-mesial gliosarcoma which directly involved the ipsilateral oculomotor nerve. Reported cases of gliomas with direct involvement of a cranial nerve, from the third to the twelfth, are very rare, whit no cases of gliosarcoma described. Because of its rarity, sometimes this entity is not considered as diagnostic hypothesis and is misdiagnosed, both during preoperative diagnostic evaluation and during the surgery. Gliosarcoma is a strong challenge for neurosurgeons and neurooncologists because of low incidence, poor prognosis and limited reported cases on literature. This case shows unique features for localization, pattern of growth and clinical presentation.

show abstract

Section: Discussionmentioning

confidence: 99%

Gliosarcoma with direct involvement of the oculomotor nerve: Case report and literature review

Corvino¹,

Peca²,

Corazzelli³

et al. 2022

Radiology Case Reports

View full text Add to dashboard Cite

show abstract

“…The term exophytic refers to lesions that meet the following two criteria: (i) Observation in preoperative magnetic resonance imaging studies outside the anatomic limits of the brain surface and (ii) trans-surgical identification of pial and arachnoid invasion, with tumor growth through cisterns [ 5 ]. There are sporadic reports in adults about astrocytic lesions of a high degree of exophytic behavior [ 6 , 7 ], and few series of isolated cases in the pediatric population, in which their location has been infratentorial.…”

Section: Discussionmentioning

confidence: 99%

Anaplasic astrocytoma with exophytic growth in Sylvian fissure in a pediatric patient: a case report

Guerra-Mora

Bravo-Ángel

Hernández-Reséndiz

et al. 2018

Journal of Surgical Case Reports

View full text Add to dashboard Cite

Gliomas are the most frequent supratentorial intracranial tumors in the pediatric population. Usually, they are intra-axial lesions with a characteristic image pattern, however, there are few reported cases of gliomas with exophytic growth. There are no previous reports in the literature of gliomas with exophytic growth in the Sylvian fissure. Fourteen year-old female patient who started with seizures. In imaging studies, a neoplasic mass with an exophytic portion in the left Sylvian fissure was found. Macroscopically, total resection was performed, definitive diagnosis was anaplastic astrocytoma. She presented recurrence and is currently receiving adjuvant treatment. Supratentorial gliomas with exophytic growth are extremely rare. We report the first case in the pediatric population, and we consider it is important to know its imaging and macroscopic characteristics for its initial management and to take it into account as a differential diagnosis of exophytic lesions.

show abstract

“…A review of the literature revealed only three cases of high grade gliomas presenting as complete third nerve paresis. [ 2 3 4 ] The most likely mechanism of oculomotor nerve paresis seems to be from the direct compression by the tumor. In our case, the tumor was directly compressing the third nerve and was markedly adherent to it.…”

Section: Discussionmentioning

confidence: 99%

“…A review of literature identified only three cases of gliomas presenting with isolated complete ipsilateral third nerve paresis. [ 2 3 4 ] We are reporting an unusual case of high grade glioma presenting as isolated complete third nerve paresis.…”

Section: Introductionmentioning

confidence: 99%

Isolated third nerve palsy: A rare presentation of high grade glioma

Singh

2016

Asian J Neurosurg

View full text Add to dashboard Cite

High grade gliomas account for almost one-third of primary central nervous system neoplasm, mainly in adults with a mean age of 41 years. They usually present with symptoms of raised intracranial pressure such as headache, vomiting, and seizures. We report a case of 55-year-old male presenting with right side complete third nerve palsy. Magnetic resonance imaging revealed an intraaxial tumor of the right medial temporal lobe. The tumor was removed grossly, and the histological diagnosis was anaplastic astrocytoma (WHO grade 3). We discuss clinical presentation of this case along with pertinent literature.

show abstract

Isolated Oculomotor Nerve Paresis in Anaplastic Astrocytoma With Exophytic Invasion

Cited by 8 publications

References 17 publications

Gliosarcoma with direct involvement of the oculomotor nerve: Case report and literature review

Gliosarcoma with direct involvement of the oculomotor nerve: Case report and literature review

Anaplasic astrocytoma with exophytic growth in Sylvian fissure in a pediatric patient: a case report

Isolated third nerve palsy: A rare presentation of high grade glioma

Contact Info

Product

Resources

About