Isolated Non-ascitic Peritoneal Carcinomatosis from Metastatic Prostate Cancer

Abstract

Prostate cancer most commonly metastasizes to bone, lung and liver. Omental metastasis of prostate cancer is extremely rare, with only a few cases reported in the literature, many of which have associated ascites. We present a case of non-ascitic omental metastasis of prostate cancer without any bone metastases. Furthermore, this patient has had two negative measurements of circulating tumor cells (CTCs) in the blood, suggesting a non-hematogenous route of metastasis to the omentum.

Isolated peritoneal carcinomatosis from metastatic castration-resistant prostate cancer and associated biliary obstruction: A case report

“…In reviewed MCRPC cases, chemotherapeutic agents (such as Docetaxel) and corticosteroids had some impact on the extent of peritoneal disease. Also, Sheng et al 5 reported the case of a 60 year-old male who underwent total omentectomy, with a subsequent drop in PSA from 11.8 to 1.8 ng/ml. This patient then had a rise in PSA and recurrence of peritoneal nodules, which responded well to ADT.…”

Two Unique Cases of Peritoneal Carcinomatosis Following Robotic Assisted Radical Prostatectomy

“…We are the first to report two cases of metastatic peritoneal carcinomatosis of prostate cancer from a high-volume single institution. Table 1 compares our cases to previous cases from the literature (1,2,3,4,5,6,7,8,9,10,11). Our cases are unique in several ways.…”

“…Peritoneal carcinomatosis from prostate cancer, with and without evidence of other metastatic sites, is extremely rare and not well studied. A handful of case reports describe dissemination at the time of cancer diagnosis as well as after treatment (1,2,3,4,5,6). These presentations vary widely, with most patients presenting with new-onset malignant ascites.…”

Isolated non-ascitic peritoneal carcinomatosis after robotic radical prostatectomy for prostate cancer: A case report

“…Prostate adenocarcinoma metastasizes in 35% of cases after radical prostatectomy, the bones being the most targeted organ (90%). 4 It is known that it can metastasizes elsewhere as in the lung, the liver or even in the peritoneum. 4 Nonetheless, peritoneal dissemination without any other organ involved especially the bone is very rare.…”

“… 4 It is known that it can metastasizes elsewhere as in the lung, the liver or even in the peritoneum. 4 Nonetheless, peritoneal dissemination without any other organ involved especially the bone is very rare. In fact, only 7 cases of histologically-proven peritoneal metastases following laparoscopic surgery, whether robot-assisted or not, are reported in the literature in the absence of other metastatic lesions.…”