Isolated Neurofibroma of the Orbit: Case Report and Literature Review

Braich, Puneet S.; Donaldson, Jared C.; Bajaj, Gurtej S.; Bearden, William O.

doi:10.1097/iop.0000000000000930

Cited by 10 publications

(3 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Isolated neurofibromas of the orbit (also known as localized, solitary, or circumscribed) is the term used to refer to those neurofibromas of the orbit, which occur without a systemic diagnosis of NF1, previously known as von Recklinghausen disease [ 9 ]. Overall, neurofibromas are uncommon in adults, 1-3% of all space-occupying lesions of the orbit [ 2 , 10 ].…”

Section: Discussionmentioning

confidence: 99%

Localized Bilateral Superior and Inferior Orbital Neurofibroma in the Absence of Neurofibromatosis

Rojas-Correa

Bengoa-González

Mencía‐Gutiérrez

et al. 2021

Case Reports in Ophthalmological Medicine

View full text Add to dashboard Cite

Localized or isolated neurofibromas are peripheral nerve sheath tumors. They are rare in the orbit and occur without a systemic neurofibromatosis. There are few cases of bilateral tumors reported but none affecting both supraorbital and infraorbital nerves. We report a 45-year-old female who presented an extraconal mass in the right orbit as an incidental finding in a head computer tomography, without ocular symptoms. Magnetic resonance image showed a well-defined oval mass in the right supraorbital and infraorbital nerves, of similar characteristics, as well as smaller masses in the left supraorbital and infraorbital nerves. A progressive increase in size of the left supraorbital and infraorbital tumor motivated their surgical excision. The histological result was compatible with a neurofibroma. These uncommon orbital tumors are slow growing and affect the sensory nerves of the trigeminal nerve. Neurofibromas usually present progressive symptoms due to the orbital mass, proptosis, or visual changes although not in this case. Surgical removal is the only definitive treatment.

show abstract

Section: Discussionmentioning

confidence: 99%

Localized Bilateral Superior and Inferior Orbital Neurofibroma in the Absence of Neurofibromatosis

Rojas-Correa

Bengoa-González

Mencía‐Gutiérrez

et al. 2021

Case Reports in Ophthalmological Medicine

View full text Add to dashboard Cite

show abstract

“…Neurofibrome treten oft multilokulär und häufig im Rahmen einer Neurofibromatose I auf [381]. Betroffen ist das Kindesalter.…”

Section: Benigne Tumorenunclassified

Interdisziplinäre Therapie der Erkrankungen der Orbita

Eckstein,

Welkoborsky

2024

Laryngorhinootologie

View full text Add to dashboard Cite

ZusammenfassungDie Diagnostik und Therapie von Erkrankungen der Orbita ist eine interdisziplinäre Aufgabe, an der u.a. die Fachdisziplinen HNO-Heilkunde, Augenheilkunde, Radiologie, Strahlentherapie, MKG-Chirurgie, Endokrinologie und Pädiatrie beteiligt sind. Der vorliegende Übersichtsartikel stellt eine Zusammenstellung der häufigsten Erkrankungen dar, mit denen die Fachdisziplinen HNO-Heilkunde und Augenheilkunde interdisziplinär befasst sind. Es werden die akuten entzündlichen Erkrankungen incl. orbitaler Komplikationen, die autoimmunologischen Erkrankungen der Orbita incl. der endokrinen Orbitopathie, und die tumorösen Erkrankungen besprochen. Neben der Diagnostik und der Beschreibung der Klinik wird besonderes Augenmerk auf die interdisziplinäre Therapie gelegt. Abgerundet wird der Übersichtsartikel mit der Beschreibung der wichtigsten chirurgischen Zugangswege zur Orbita, ihre Indikationen und mögliche Komplikationen. Die Autoren haben versucht, trotz der knappen Darstellung die relevanten Fakten zu beschreiben.

show abstract

“…Plexiform neurofibroma is classically associated with neurofibromatosis type I (NF1). However, there are relatively few cases that involve isolated neurofibroma of the orbit of varying pathologies (myxoid, plexiform, diffuse) in the absence of clinical criteria of NF1 1 . Plexiform and diffuse neurofibromas usually present in childhood; however, isolated neurofibroma of the orbit with overlying hypertrichosis appears to be a rare finding 2, 3, 4, 5.…”

Section: Introductionmentioning

confidence: 99%