Isolated Myeloid Sarcoma of the Maxillary Sinus: A Case Report and Review of Literature

Young, Chi-Kuang

doi:10.4172/2157-7099.1000234

Cited by 3 publications

(1 citation statement)

References 17 publications

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“…2 Isolated myeloid sarcoma of paranasal sinuses are rare. 7 Diagnosis tends to be difficult especially if the tumor does not occur in the context of AML and manifests in a very rare site. We are presenting such a rare case.…”

Section: Introductionmentioning

confidence: 99%

Myeloid sarcoma of maxillary sinus

2020

IJPO

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We report a case of isolated myeloid sarcoma (MS) of maxillary sinus in a patient who had no evidence of leukemia at the time of diagnosis of MS. A 39 year old healthy woman presented with right cheek swelling of one year duration. CT scan of paranasal sinuses showed an illdefined, heterogenously enhancing soft tissue density lesion in relation to right maxilla. CT findings suggested the possibility of inflammatory phlegmon with osteomyelitis. Biopsy showed a malignant round cell neoplasm which on immunohistochemistry was confirmed to be myeloid sarcoma.On follow up, one month later her peripheral blood and bone marrow showed features of Acute Myeloid Leukemia which was confirmed to be AML-M2 on Flow cytometry. The diagnosis of myeloid sarcoma has always been difficult especially when it is presenting in an unusual location in a non leukemic patient.

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Section: Introductionmentioning

confidence: 99%

Myeloid sarcoma of maxillary sinus

2020

IJPO

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Surgical Treatment of Maxillary Antrum Neoplasms

Abdulkareem

Aftan²

2018

Journal of Craniofacial Surgery

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Paranasal sinus cancers comprise about 0.3% of all cancers and 80% of these lesions arise in the maxillary sinus. A masquerading primary sinus tumour represents a therapeutic challenge as most patients with maxillary antrum cancer are diagnosed with advanced disease. However, distant metastases rarely occur. We examined the clinical outcome of patients with antrum neoplasms. Medical records were obtained for all patients diagnosed with a sinus malignancy between July 2009 and January 2014. During this period, 41 patients with maxillary tumours were treated, among which 9 patients received a maxillectomy. There were 21 male and 20 female patients. All patients underwent computed tomography or magnetic resonance imaging. The most common complications were postoperative epistaxis and swallowing difficulty. The treatment of maxillary antrum tumours is complicated and needs advancements to improve early presentation, timely diagnosis, and better management outcomes.

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A Case of Myeloid Sarcoma in the Nasal Cavity Occurred in the Patient with Leukemic Transformation in Myelodysplastic Syndrome

Lee¹,

Park²,

Park³

et al. 2020

Korean J Otorhinolaryngol-Head Neck Surg

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Myeloid sarcoma is characterized by the presence of myeloid blasts at an extramedullar site that disrupts the normal architecture of the organ. Many of these cases are associated with acute myeloid leukemia, chronic myeloid leukemia, myelodysplastic syndrome, or occur in de novo. It occurs most commonly in skin, lymph node, gastrointestinal tract, bone, soft tissue but, rarely in head and neck; especially in nasal cavity. Therefore, it is often misdiagnosed as a different disease: most commonly as lymphoma. Here we report a rare case of myeloid sarcoma in the nasal cavity that occurred in a patient with leukemic transformation with myelodysplastic syndrome, provided with literature review.

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Isolated Myeloid Sarcoma of the Maxillary Sinus: A Case Report and Review of Literature

Cited by 3 publications

References 17 publications

Myeloid sarcoma of maxillary sinus

Myeloid sarcoma of maxillary sinus

Surgical Treatment of Maxillary Antrum Neoplasms

A Case of Myeloid Sarcoma in the Nasal Cavity Occurred in the Patient with Leukemic Transformation in Myelodysplastic Syndrome

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