Isolated Metastasis of Hepatocellular Carcinoma to the Gallbladder Mimicking Gallbladder Carcinoma: A Case Report

Choi, Mansu; Kwon, Heejin; Cho, Jin-Han; Oh, Jongyeong; Nam, Kyung Jin; Han, Sang-Yeong; Jeong, Jin–Sook

doi:10.3348/jksr.2012.66.5.459

J Korean Soc Radiol

2012

DOI: 10.3348/jksr.2012.66.5.459

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Isolated Metastasis of Hepatocellular Carcinoma to the Gallbladder Mimicking Gallbladder Carcinoma: A Case Report

Mansu Choi

Heejin Kwon

Jin-Han Cho

et al.

Abstract: Metastasis of hepatocellular carcinoma (HCC) to the gallbladder (GB) through direct invasion is relatively common; on the other hand, isolated metastasis of HCC to the GB is extremely rare. We report here the radiologic finding of an isolated metastasis of HCC to the GB appearing as a polypoid mass in the GB lumen mimicking GB cancer in a patient treated for HCC.

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2023

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Case report and literature review: Isolated HCC- recurrence in gallbladder after curative resection

Zhang¹,

Ma²,

Zhou³

et al. 2023

Front. Surg.

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BackgroundLiver resection (LR) is considered the mainstay treatment for eligible patients with hepatocellular carcinoma (HCC) and provides a 5-year overall survival (OS) of 60%–80%. However, the recurrence rate within five years after LR remains high, ranging from 40% to 70%. Recurrence in gallbladder after liver resection is extremely rare. Here, we present a case of isolated recurrence in gallbladder after curative resection of HCC and review the relevant literature. No similar cases have been reported before.Case presentationA 55-year-old male patient was diagnosed with HCC in 2009 and subsequently underwent a right posterior sectionectomy of the liver. In 2015, the patient underwent liver tumor radiofrequency ablation and three transarterial chemoembolization (TACE) procedures in succession for HCC recurrence. In 2019, a gallbladder lesion was detected by computed tomography (CT) without perceivable intrahepatic focus. We performed an en bloc resection of the gallbladder and hepatic segment IVb. The pathological biopsy suggested that the gallbladder tumor was moderately differentiated HCC. The patient survived more than 3 years in good condition, and there were no signs of tumor recurrence.ConclusionsIn patients with isolated gallbladder metastasis, if the lesion can be resected en bloc without remnants, surgery should be the preferred option. Both postoperative molecularly targeted drugs and immunotherapy are expected to improve the long-term prognosis.

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Case report and literature review: Isolated HCC- recurrence in gallbladder after curative resection

Zhang¹,

Ma²,

Zhou³

et al. 2023

Front. Surg.

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Isolated Metastasis of Hepatocellular Carcinoma to the Gallbladder Mimicking Gallbladder Carcinoma: A Case Report

Cited by 1 publication

References 5 publications

Case report and literature review: Isolated HCC- recurrence in gallbladder after curative resection

Case report and literature review: Isolated HCC- recurrence in gallbladder after curative resection

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