Isolated lipodystrophy, a form of mesenteric tumor

CT Evaluation of Mesenteric Panniculitis

“…The fatty halo surrounding nodules and vessels exhibited CT attenuation values suggestive of normal fat. A similar halo representing normal fat interposed between a central lymphoid aggregate or lymph node and a zone of peripherally oriented macrophages has been previously described on histopathology [4,7]. The fatty tissue of mesenteric panniculitis was hyperattenuated when compared with that of the retroperitoneal fat.…”

“…Various terms resulting in considerable confusion are used to describe the disease. Sclerosing mesenteritis [16], liposclerotic mesenteritis [17], mesenteric lipodystrophy [7], and mesenteric variety of Weber-Christian disease [18] are more commonly used.…”

“…Laboratory findings, including elevation in erythrocyte sedimentation rate and anemia, are absent or nonspecific. Complete resection of the mass is usually impossible and is generally considered to be of no benefit [5,7]. Because reports in the literature focus on histologic findings, CT features of this disease have been only sporadically presented [8][9][10][11][12][13].…”

Systemic Weber-Christian disease

“…A close resemblance to the histological appearances of Weber-Christian disease is seen in 'isolated mesenteric lipodystrophy' (Crane, Aguilar, and Grimes, 1955;Rogers, Demetrakopoulos, and Hyamns, 1961;Herrington, Edwards, and Grossman, 1961) and in 'retractile mesenteritis' (Jura, 1924;Tedeschi and Author Botta, 1962). These may be interpreted as systemic Weber-Christian disease without panniculitis.…”

CT Findings in Sclerosing Mesenteritis (Panniculitis): Spectrum of Disease

“…Surgical resection is sometimes attempted, but complete removal is often difficult due to vessel compromise and may be of no clear benefit to the patient (10,25). In cases of colonic involvement by sclerosing mesenteritis, a colostomy may be necessary because complete surgical resection is often not technically possible.…”