Isolated left ventricular non-compaction cardiomyopathy complicated by acute ischemic stroke: A rare case repor

Ahmed, Said Abdirahman; Karataş, Mesut; Öcal, Lütfi; Hassan, Mohamed Sheikh; Mohamud, Mohmed Abdullahi; Hassan, Mohamed Omar; Dirie, Abdirahman Mohamed Hassan; Waberi, Mohamud Mire; Ali, Abdijalil Abdullahi

doi:10.1016/j.amsu.2022.104543

Cited by 6 publications

(7 citation statements)

References 12 publications

(13 reference statements)

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“…In 267 individuals with de nite or possible IE, sepsis (n = 23, 46%), multi-organ failure (n = 8, 16%), heart failure (n = 4, 16%), and sudden death (n = 4) were the primary causes of mortality [12] . Although transthoracic echocardiography is an excellent tool for infective endocarditis diagnosis, it still has a negative rate of about 50% even though the clinical suspicion of endocarditis is high [13,17] , it still has negative. Factors that may increase the downside of TTE include the absence of staphylococcal bacteremia and fungemia, as well as cultures of negative etiologies [14] .…”

Section: Discussionmentioning

confidence: 99%

Post-cardiac catheterization infective endocarditis with flail mitral valve leaflets: an interesting and rare case

Ahmed¹,

Mohamud²,

Waberi³

et al. 2023

Preprint

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Endocarditis is a life-threatening infection of the endocardium (inner lining of the heart). It usually affects the left-sided valves more than the right-sided valves and presents classically with a new murmur, fever, and peripheral stigmata. Though in the modern era, we have better antibiotics, better diagnostic imaging, and surgery that might cure infectious endocarditis (IE), it still carries significant mortality and morbidity. Here we present a 52-year-old male patient with hypertension and ischemic heart disease who presented with shivering, fever, and confusion for 2 days, fourteen days after cardiac intervention (PCI). Further trans-esophageal echocardiography was done due to the patient’s fulfillment of three minor and one major of Duke's criteria. Trans-esophageal echocardiography revealed flailing posterior mitral valve leaflets, 1.1 x 0.60 cm of vegetation, and severe eccentric mitral regurgitation. The patient was managed with vancomycin and gentamicin and referred to the cardiovascular surgery center. Post-PCI infective endocarditis is a rare and often missed diagnosis, so there should be a high level of suspension for those who present with signs and symptoms compatible with infective endocarditis.

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Section: Discussionmentioning

confidence: 99%

Post-cardiac catheterization infective endocarditis with flail mitral valve leaflets: an interesting and rare case

Ahmed¹,

Mohamud²,

Waberi³

et al. 2023

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“… 22 Patients with ejection fractions below 40%, anterior wall MI, and LV aneurysms had a higher risk of developing an LV thrombus. 23 , 24 …”

Section: Discussionmentioning

confidence: 99%

“…22 Patients with ejection fractions below 40%, anterior wall MI, and LV aneurysms had a higher risk of developing an LV thrombus. 23,24 Left ventricular (LV) thrombus development due to stasis brought on by localized or systemic cardiac dysfunction is most often linked to myocardial infarction (MI) and dilated cardiomyopathy (DCM). Between 1% and 2.5% of patients with acute MI get stroke within 4 weeks, with 50% happening during the first 5 days.…”

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confidence: 99%

Analysis of Echocardiographic Findings of Patients with Acute Ischemic Stroke Admitted to a Tertiary Care Hospital in Mogadishu, Somalia

Hassan¹,

Waberi²,

Sidow³

et al. 2023

IJGM

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Background and Aims:The etiological investigation of the potential cardiac source of acute ischemic stroke is important for the secondary prevention of recurrent and future embolization. Transthoracic echocardiography is one of the most useful investigations for the assessment of the potential cardiac etiology of ischemic stroke. Our aim is to evaluate echocardiographic findings in patients with acute ischemic stroke admitted to a tertiary care hospital in Mogadishu, Somalia. Methods: This was a retrospective observational study conducted in the neurology department of a tertiary care hospital in Mogadishu, Somalia. We enrolled 315 patients with acute ischemic stroke admitted to the hospital who had undergone transthoracic echocardiography between March 2019 and March 2022. We analyzed transthoracic echocardiography findings, ischemic stroke subtypes, and their associated comorbidities. We also compared the demographic data, comorbidity, and survival status of patients with abnormal echo findings to those with normal echo findings. Findings: The mean age of patients was 62±12 years. Co-morbidities were present in about 251 (80%) of the subjects, hypertension was the most common comorbidity 99 (31.4%), followed by diabetes 72 (23%), and hyperlipidemia 37 (11.7%). Overall cardiac pathology in this study was 170 (54%). Forty-seven (15%) of the patients had low ejection fraction on transthoracic echocardiography. Male patients had slightly less left ventricular systolic dysfunction than female patients. 100 (32%) had left ventricular diastolic dysfunction (LVDD), while 113 (36%) had left ventricular hypertrophy (LVH). Patients with hypertension and diabetes had more echo abnormalities compared to others (P-values of 0.047 and 0.024, respectively). More abnormal echo findings were seen in patients who died during hospitalization than in those who survived (P = 0.008). Severe left ventricular systolic dysfunction was associated with higher mortality (P < 0.001). Conclusion:Most patients with stroke in this study had abnormal echocardiograms; however, only a few had cardioembolic strokes. Abnormalities in echocardiography were more common in patients who died during hospitalization than in those who survived.

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“…Agitation or acute behavioral disturbances may be the only presentations [8,6,15] . In this paper, we report a case of bilateral thalamic infarction with a history of hypertension, presenting with agitation and somnolence without corticospinal tract involvement.…”

Section: Introductionmentioning

confidence: 99%

Bilateral Paramedian Thalamic Infarct without Involvement of Corticospinal Tract

Hassan¹,

Sidow²

2022

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Introduction and importance: Bilateral thalamic infarct is a rare form of stroke. Mostly thalamic infarcts are unilateral. Occlusion of the artery of Percheron leads to bilateral thalamic infarction with or without involvement of the midbrain. In most cases, bilateral thalamic infarction leads to cognitive dysfunction, opthalmoparesis, conscious impairment, behavioral disturbance, and corticospinal dysfunction. Case Presentation: A 75-year-old male patient presented to the emergency department of our hospital with agitation and somnolence for one day. He had poorly controlled hypertension. There was no previous history of stroke, diabetes mellitus, hyperlipidemia, known cardiac disease, or smoking history. There was no seizure, recent headache, or visual disturbance. The patient was somnolent and not oriented to time, person, or place. Neurological examination did not show any focal weakness or vertical eye movement restrictions. Other systemic examinations, including those of the respiratory and cardiovascular systems, were unremarkable. Extensive laboratory investigations excluded potential metabolic, infectious, endocrine, or toxic etiologies. The patient did not have any recent history of drug misuse, including benzodiazepines. Brain MRI with diffusion-weighted imaging showed an acute bilateral thalamic infarct. Cerebral MRI angiography was unremarkable. ECG and echocardiography did not show any potential cardioembolic source. The patient was treated with low molecular weight heparin 60 mg subcutaneously, aspirin 300 mg daily, and haloperidol 5mg twice daily. After two weeks of intrahospital treatment, his condition improved (consciousness and orientation massively improved). He was discharged for outpatient neurology clinic follow up. Conclusion: Bilateral thalamic infarcts are rare presentations of posterior circulation stroke; conscious impairment, agitation, and cognitive dysfunction are the major presentations. Here we report an interesting case with hypertension diagnosed bilateral thalamic infarction without corticospinal tract involvement.

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Isolated left ventricular non-compaction cardiomyopathy complicated by acute ischemic stroke: A rare case repor

Cited by 6 publications

References 12 publications

Post-cardiac catheterization infective endocarditis with flail mitral valve leaflets: an interesting and rare case

Post-cardiac catheterization infective endocarditis with flail mitral valve leaflets: an interesting and rare case

Analysis of Echocardiographic Findings of Patients with Acute Ischemic Stroke Admitted to a Tertiary Care Hospital in Mogadishu, Somalia

Bilateral Paramedian Thalamic Infarct without Involvement of Corticospinal Tract

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