Isolated Intracranial Rosai–Dorfman Disease Mimicking Meningioma: A Case Report

Abstract

Rosai–Dorfman Disease (RDD) is a rare lymphoproliferative disease, and the occurrence of isolated intracranial RDD is extremely rare. Most cases of intracranial RDDs present as dural masses showing homogenous enhancement on MRI, which makes it difficult to differentiate these masses from meningiomas before surgery unless massive cervical lymphadenopathy is observed. We herein report a rare case of isolated intracranial RDD in a 65-year-old male. Brain MRI revealed a well-defined enhancing mass-like lesion involving the right frontal convexity and subtle diffusion restriction. However, only a subtle blush was observed on the preoperative cerebral angiogram. Although instances of isolated intracranial RDD are rare, it should be considered as a potential differential diagnosis when a dural mass with hypovascularity is visualized on the cerebral angiogram.

Dural involvement in central nervous system langerhans cells histiocytosis (LCH) on FDG PET/CT: Case report and review of CNS manifestations of LCH on PET/CT

“…High on the list of differential diagnoses when evaluating dural lesions is meningioma, which can be a source of confusion and misdiagnosis in situations of isolated dural disease [ [38] , [39] , [40] , [41] , [42] ]. Although meningiomas are not conventionally evaluated with FDG-PET, literature shows that they are typically minimal-to-moderately FDG avid, depending on grade [ 43 , 44 ].…”