Isolated hepatic tuberculosis: report of five cases and review of the literature

Kok, Kenneth Y.Y.; Yapp, S. K. S.

doi:10.1007/s005340050106

Cited by 58 publications

(45 citation statements)

References 19 publications

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“…Diffuse hepatic infiltration without recognizable pulmonary involvement was the second most common and isolated focal tuberculoma or abscess with an overall incidence of about 0.3% (Purl et al, 1994;Kok &Yapp, 1999;Lee et al, 2010). The patient presented in this case was found to have hepatic involvement without evidence of tuberculosis elsewhere; the space occupying lesion in the form of abscess is one of the rarest manifestations.…”

Section: Discussionmentioning

confidence: 80%

Isolated tubercular hepatic abscess with diffuse pattern mimicking hepatocellular carcinoma in HIV positive patient: a case report

Setime

Rwegerera

Chowdhury

2014

Tanzania J Hlth Res

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Isolated hepatic tuberculosis presenting as a mass either with or without fever can be confused with hepatocellular carcinoma. Clinical examination and laboratory investigations are not specific. Radiological investigations such as ultrasound and computed tomography cannot confirm the diagnosis; hence it is vital to always make an effort to demonstrate presence of acid fast bacilli in aspirated pus or necrotic material from a liver mass. We present a case of 50 years old male patient with HIV/AIDS who presented with non-specific symptoms without fever, clinically with hepatomegaly mimicking hepatocellular carcinoma with metastasis.

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Section: Discussionmentioning

confidence: 80%

Isolated tubercular hepatic abscess with diffuse pattern mimicking hepatocellular carcinoma in HIV positive patient: a case report

Setime

Rwegerera

Chowdhury

2014

Tanzania J Hlth Res

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“…[43], [44] In addition, Kok et al mentioned that localized liver TB represents 0.3% of 1,678 new cases of TB in their series. [45] In miliary liver TB, It is thought that Hematogenous spreading of mycobacterium TB bacilli is the way of hepatic infection; while, in localized liver TB, the TB bacilli possibly spread to hepatic tissue from the bowel through the portal vein. [41], [44] The clinical features in case of liver involvement with TB are usually nonspecific including fever, night sweats, malaise, anorexia, weight loss, and abdominal pain.…”

Section: Discussionmentioning

confidence: 99%

“…[41], [44] The clinical features in case of liver involvement with TB are usually nonspecific including fever, night sweats, malaise, anorexia, weight loss, and abdominal pain. [40], [45] In case of disseminated TB, presence of TB in other organ might give hint to diagnose liver TB. In case of absence of such clue, the diagnosis of liver TB could be highly difficult and unexpected [41] as in two of our cases of liver involvement.…”

Section: Discussionmentioning

confidence: 99%

Tuberculosis Unexpectedly Presented Along Gastrointestinal Tract in Surgical Ward

Jasim¹

2017

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Abstract:Little is known in our country particularly in Basra about tuberculous lesions affecting the gastrointestinal tract specifically solid and hallow organs such as liver, pancreas, stomach or intestine. Hence, this study aimed to report, describe and study these cases. The current study is retrospectively studied 12 patients who got tuberculous lesions along the gastrointestinal tract over the last 2 decades in Basra General Hospital (2 of them were gastric, 3 hepatic, 3 pancreatic, 3 small intestinal; one of them affecting duodenojejunal flexure, and lastly 1 perianal sinus ulcerating the nearby skin). All those patients underwent the required surgical operations. In all those patients, TB was diagnosed postoperatively by histopathology and all of them received anti-tuberculosis triple therapy for 6 months including INH, Rifampicin and Ethambutol. A long term scheduled follow up was done showing that all of them were improved except one elderly patient with TB pancreatitis died at early postoperative period. None of these cases effected with pulmonary tuberculosis previously or concomitantly. One case of hepatic tuberculosis had cervical and intra-abdominal lymphadenopathy. It is of interest to mention that extrapulmonary TB in solid and hallow organs of gastrointestinal tract should be considered when evaluating patients with gastrointestinal presentations and lesions such as ulcer, mass, abscess or perianal fistula in endemic areas and the potential for affecting these organs (along gastrointestinal tract) should be kept in mind and accounted for.

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“…3 Isolated liver TB is the rarest form of local hepatic TB, 4 which is reported to have an overall incidence of 0.3%. 5 The local type occurs through the spread of the Mycobacterium by the portal vein from the intestine. This explains the common association of hepatic involvement in patients with bowel TB.…”

Section: Discussionmentioning

confidence: 99%

Portal Hypertension Secondary to Isolated Liver Tuberculosis

Otoukesh¹,

Shahsafi²,

Tahbaz³

et al. 2012

The American Society of Tropical Medicine and Hygiene

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Abstract. In this report, we present a case of isolated liver tuberculosis (TB) as a cause of non-cirrhotic portal hypertension leading to bleeding esophageal varices. Although TB has been known to cause portal hypertension in a variety of ways, this case was notable for the presence of periportal inflammation and granulomas, also seen in hepatic schistosomiasis. Herein, we discuss isolated liver TB and the differential diagnosis of non-cirrhotic portal hypertension. In endemic areas, TB should be considered in the differential diagnosis of non-cirrhotic portal hypertension.

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Isolated hepatic tuberculosis: report of five cases and review of the literature

Cited by 58 publications

References 19 publications

Isolated tubercular hepatic abscess with diffuse pattern mimicking hepatocellular carcinoma in HIV positive patient: a case report

Isolated tubercular hepatic abscess with diffuse pattern mimicking hepatocellular carcinoma in HIV positive patient: a case report

Tuberculosis Unexpectedly Presented Along Gastrointestinal Tract in Surgical Ward

Portal Hypertension Secondary to Isolated Liver Tuberculosis

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