Isolated hepatic Tuberculosis

Azad, Khan Abul Kalam; Mallik, Uzzwal; Hossain, Mohammad Zaid; Abdullah, Shayekh; Alam, Asm Moinul; Sarker, Partha S.

doi:10.3329/jdmc.v23i1.22706

Cited by 3 publications

(4 citation statements)

References 4 publications

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“…It accounted for 5.4% of all tuberculosis cases admitted in the institution during the study period which is higher than the 1.2% of diagnosed TB patients at a hospital in South Africa. 10 The Philippine General Hospital is a tertiary medical center where patients with more severe liver conditions are referred. In 2010, tuberculosis was the sixth leading cause of death (26.3 deaths/100,000 population) 8 in the country and was the third highest cause of mortality among immunizable diseases.…”

Section: Discussionmentioning

confidence: 99%

Features and Outcome of Hepatobiliary Tuberculosis among Filipino Children: Report of a Six-year Experience

Capul¹,

Gregorio²,

Gonzales³

2020

Acta Med Philipp

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Background. The features and outcome of hepatobiliary tuberculosis (HBTB) have not been extensively reportedin children. Objective. To describe the clinical, biochemical, radiologic, microbiologic and histologic features and outcome ofchildren diagnosed with HBTB. Methods. Data of HBTB patients aged 0-18 years were collected by review of medical records and as they wereadmitted. Cases were classified as bacteriologically-confirmed (positive AFB smear, TB culture or PCR of bile/livertissue) or clinically-diagnosed (clinical, histologic and/or radiologic evidence). Results. A total of 36 patients were included (mean age: 13yrs; 64% males): three bacteriologically-confirmed and33 clinically-diagnosed. Most common signs/symptoms were weight loss (69%), fever (67%), hepatomegaly (61%)and jaundice (53%). Of the total, 68% had hypoalbuminemia, 50% increased transaminases and 47% prolongedprothrombin time. Fifteen (42%) patients were AFB positive on various microbiologic specimens. Most commonimaging finding was hepatic calcification (64%). Of 11 patients with liver biopsy, seven (64%) had chronic/granulomatous inflammation. All 36 were managed medically. Eight were lost to follow up, six died, and 22 (61%)are alive, nine with complete resolution of liver disease. Conclusion. Hepatobiliary tuberculosis presents with non-specific clinical and biochemical findings. Severalinvestigations are necessary to confirm the diagnosis. Overall response to anti-TB treatment is satisfactory withpossible resolution of liver disease.

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Section: Discussionmentioning

confidence: 99%

Features and Outcome of Hepatobiliary Tuberculosis among Filipino Children: Report of a Six-year Experience

Capul¹,

Gregorio²,

Gonzales³

2020

Acta Med Philipp

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“…In focal tuberculosis, large tumor-like tuberculoma is formed by coalesces of various size granuloma. Caseating and liquefaction necrosis occur within tubercular granuloma and to form tubercular abscess [3] (Figures 1& 2). In world literature, 30-50 years are the common age group and usually presents with fever (50-90%), abdominal pain (45-66%), and hepatomegaly in localized hepatic TB [4,5].…”

Section: Discussionmentioning

confidence: 99%

“…Presenting symptoms in these settings are mainly those of military tuberculosis [2]. A South African study showed that hepatic tuberculosis considered for 1.2% of all cases of tuberculosis diagnosed at a general hospital [3]. In Bangladesh, there are few cases of hepatic tuberculosis reported to date.…”

Section: Introductionmentioning

confidence: 99%

Localized Hepatic Tuberculosis in a 14-Year Old Bangladeshi Girl: A Case Report

Islam¹,

Hassan²,

Roy³

et al. 2020

BJSTR

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“…It is more difficult for a clinician to diagnose as in most cases it is frequently confused with pyogenic or amoebic liver abscess or a hepatoma [3]. Only a few cases have been reported in Bangladesh till date [4][5][6][7]. Recently we came across tubercular liver abscess in an immunocompromised patient without any primary foci of infection which was really a diagnostic challenge for us.…”

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confidence: 99%

Isolated Tubercular Liver Abscess: A Rare Case Report

Ma¹,

M²,

Sa³

2023

JSWMC

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Background: Tuberculosis (TB) continues to be a global public health problem, particularly in the developing countries [1]. It usually involves organs like lungs and/or gastrointestinal (GI) tract [2]. Hepatic involvement is usually associated with miliary tuberculosis which is one of the most characteristic manifestations of tuberculosis. Isolated liver abscess without any primary infection is a rare clinical entity. It is more difficult for a clinician to diagnose as in most cases it is frequently confused with pyogenic or amoebic liver abscess or a hepatoma [3]. Only a few cases have been reported in Bangladesh till date [4-7]. Recently we came across tubercular liver abscess in an immunocompromised patient without any primary foci of infection which was really a diagnostic challenge for us. Objectives: The objective of reporting this case is to aware clinicians about the uncommon presentation of a common disease like tuberculosis. This will be an eye-opening experience for clinicians and help in formulating differentials in the workup of patient with pyrexia due to non-resolving liver abscess.

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Isolated hepatic Tuberculosis

Abstract: Abstract

Cited by 3 publications

References 4 publications

Features and Outcome of Hepatobiliary Tuberculosis among Filipino Children: Report of a Six-year Experience

Features and Outcome of Hepatobiliary Tuberculosis among Filipino Children: Report of a Six-year Experience

Localized Hepatic Tuberculosis in a 14-Year Old Bangladeshi Girl: A Case Report

Isolated Tubercular Liver Abscess: A Rare Case Report

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