Isolated Fungal Sphenoid Sinusitis After Endonasal Transsphenoidal Approach

Chung, Hyo Jin; Lee, Hoyoung; Oh, Jangwon; Chang, Jung Hyun

doi:10.1177/0145561320961205

Cited by 2 publications

(2 citation statements)

References 8 publications

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“…Five patients required further endoscopic sphenoidotomy, fungal balls were identified in three of the patients, mucocele formation was encountered in one case, and one presented with infected fat graft. Chung et al [28] reported a 56-year-old female patient diagnosed with isolated fungal sphenoid sinusitis 10 years after a transsphenoidal approach for pit-NETs and a history of skull base repair 5 years prior to the event. She presented with symptoms of postnasal drip and foul odor, and endoscopic examination revealed purulent discharge and swollen mucosa of sphenoid sinus.…”

Section: Discussionmentioning

confidence: 99%

Risk Factors for Isolated Sphenoid Sinusitis after Endoscopic Endonasal Transsphenoidal Pituitary Surgery

Chang,

Tsao,

Chuang

et al. 2024

Diagnostics

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(1) Background: Transsphenoidal pituitary surgery can be conducted via microscopic or endoscopic approaches, and there has been a growing preference for the latter in recent years. However, the occurrence of rare complications such as postoperative sinusitis remains inadequately documented in the existing literature. (2) Methods: To address this gap, we conducted a comprehensive retrospective analysis of medical records spanning from 2018 to 2023, focusing on patients who underwent transsphenoidal surgery for pituitary neuroendocrine tumors (formerly called pituitary adenoma). Our study encompassed detailed evaluations of pituitary function and MRI imaging pre- and postsurgery, supplemented by transnasal endoscopic follow-up assessments at the otolaryngology outpatient department. Risk factors for sinusitis were compared using univariate and multivariate logistic regression analyses. (3) Results: Out of the 203 patients included in our analysis, a subset of 17 individuals developed isolated sphenoid sinusitis within three months postoperation. Further scrutiny of the data revealed significant associations between certain factors and the occurrence of postoperative sphenoid sinusitis. Specifically, the classification of the primary tumor emerged as a notable risk factor, with patients exhibiting nonfunctioning pituitary neuroendocrine tumors with 3.71 times the odds of developing sinusitis compared to other tumor types. Additionally, postoperative cortisol levels demonstrated a significant inverse relationship, with lower cortisol levels correlating with an increased risk of sphenoid sinusitis postsurgery. (4) Conclusions: In conclusion, our findings underscore the importance of considering tumor classification and postoperative cortisol levels as potential predictors of postoperative sinusitis in patients undergoing transsphenoidal endoscopic pituitary surgery. These insights offer valuable guidance for clinicians in identifying at-risk individuals and implementing tailored preventive and management strategies to mitigate the occurrence and impact of sinusitis complications in this patient population.

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Section: Discussionmentioning

confidence: 99%

Risk Factors for Isolated Sphenoid Sinusitis after Endoscopic Endonasal Transsphenoidal Pituitary Surgery

Chang,

Tsao,

Chuang

et al. 2024

Diagnostics

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“…The fungal hyphae in the nasal mucosa cannot be cleared due to an anomaly in the mucociliary clearance process. Furthermore, less ventilation would cause the pH to drop and encourage the growth of fungi [ 8 ].…”

Section: Discussionmentioning

confidence: 99%

Atypical headache by isolated sphenoid fungal sinusitis: A rare case

Aditomo

2024

International Journal of Surgery Case Reports

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Isolated Fungal Sphenoid Sinusitis After Endonasal Transsphenoidal Approach

Cited by 2 publications

References 8 publications

Risk Factors for Isolated Sphenoid Sinusitis after Endoscopic Endonasal Transsphenoidal Pituitary Surgery

Risk Factors for Isolated Sphenoid Sinusitis after Endoscopic Endonasal Transsphenoidal Pituitary Surgery

Atypical headache by isolated sphenoid fungal sinusitis: A rare case

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