Isolated cutaneous mucormycosis in a pediatric renal transplant recipient

Downie, Mallory L.; Alghounaim, Mohammad; Davidge, Kristen M.; Yau, Yvonne; Walsh, Thomas J.; Pope, Elena; Somers, Gino R.; Waters, Valerie; Robinson, Lisa A.

doi:10.1111/petr.13172

Cited by 8 publications

(3 citation statements)

References 12 publications

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“…We have observed that wound margins may appear clinically and histologically intact while still having viable organisms present. We therefore have used a system of intraoperative assessment of resected tissue margins sent by the surgical team to the clinical microbiology laboratory for fluorescent microscopy using calcofluor wet mounts [40,41].…”

Section: Principles Of Managementmentioning

confidence: 99%

Necrotizing Mucormycosis of Wounds Following Combat Injuries, Natural Disasters, Burns, and Other Trauma

Walsh

Hospenthal

Petraitis

et al. 2019

JoF

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Necrotizing mucormycosis is a devastating complication of wounds incurred in the setting of military (combat) injuries, natural disasters, burns, or other civilian trauma. Apophysomyces species, Saksenaea species and Lichtheimia (formerly Absidia) species, although uncommon as causes of sinopulmonary mucormycosis, are relatively frequent agents of trauma-related mucormycosis. The pathogenesis of these infections likely involves a complex interaction among organism, impaired innate host defenses, and biofilms related to traumatically implanted foreign materials. Effective management depends upon timely diagnosis, thorough surgical debridement, and early initiation of antifungal therapy.

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Section: Principles Of Managementmentioning

confidence: 99%

Necrotizing Mucormycosis of Wounds Following Combat Injuries, Natural Disasters, Burns, and Other Trauma

Walsh

Hospenthal

Petraitis

et al. 2019

JoF

Self Cite

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“…Intra operative frozen sections can be used and histopathological examination can be done to confirm adequate excision, however the sensitivity of frozen section is only around 68.4%. 10 Both our patients did not undergo intra-op frozen section. They underwent debridement until all subcutaneous necrotic tissue was removed, following which they underwent wound closure using rotational flap and split skin grafting techniques.…”

Section: Discussionmentioning

confidence: 89%

Post traumatic cutaneous mucormycosis: a diagnostic dilemma

Nair¹,

Gowthaman²,

Bagalgotkar³

et al. 2021

Int Surg J

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The incidence of mucormycosis, an invasive fungal disease, is more in the developing countries, especially among the immunocompromised individuals. However, this disease can also occur in those without any predisposing factors. In the developed countries, those undergoing haematopoetic stem cell transplantation were more prone to developing this disease. There can be varied presentations of mucormycosis. It could be rhinocerebral, pulmonary, cutaneous, gastrointestinal or even disseminated forms. Post traumatic mucormycosis is infrequently reported and is often difficult to diagnose earlier due to its unusual presentation. In this case report, we describe two patients who acquired cutaneous mucormycosis following traumatic wounds and how they characteristically presented with 3 zones which was identified by us and has not been reported of earlier. This can help in diagnosis of this condition earlier and to follow the treatment protocol accordingly and prevent the morbidity and mortality associated with this disease.

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“…Intraoperative assessment of margins by fluorescent microscopy has been advocated for that. 18 Medical management includes use of antifungal drugs. Liposomal amphotericin B (LAB) is the drug of choice and the dose should be at least 5 mg/kg/day.…”

Section: Discussionmentioning

confidence: 99%

Neuromucormycosis of Posterior Tibial Nerve: A Rare Presentation of Mucormycosis

Tajudeen

Shaikh

Balasubramanian

et al. 2021

The International Journal of Lower Extremity Wounds

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Opportunistic fungal infections are known to occur in immunocompromised patients. Mucormycosis is one of the most common opportunistic fungal infections with significant mortality rates. In this article, we present a case of an adult female, a known diabetic who presented with fever and pus discharge from the amputation site of toes in the left foot with blackening of the foot. Examination revealed gangrenous changes of the left foot with no distal pulses palpable. Computed tomography angiogram revealed no flow of blood in distal vessels of the left lower limb. Left below knee guillotine amputation was done. Intraoperative biopsy of the neurovascular bundle revealed invasive neuromucormycosis. She was started on liposomal amphotericin B. The wound started granulating after a few days with serial dressings and the patient was planned for split skin grafting.

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Isolated cutaneous mucormycosis in a pediatric renal transplant recipient

Cited by 8 publications

References 12 publications

Necrotizing Mucormycosis of Wounds Following Combat Injuries, Natural Disasters, Burns, and Other Trauma

Necrotizing Mucormycosis of Wounds Following Combat Injuries, Natural Disasters, Burns, and Other Trauma

Post traumatic cutaneous mucormycosis: a diagnostic dilemma

Neuromucormycosis of Posterior Tibial Nerve: A Rare Presentation of Mucormycosis

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