Isolated Craniocervical Dystonia Without Initial Neuropsychiatric Manifestations Associated with NMDA‐Receptor Antibodies

Isolated Dystonia with NMDAR Antibodies: Expanding the Phenotype or Illustrating the Intricacies of Antibody Testing?

“…In this issue, two groups report the cases of two young women with isolated (cranio-) cervical dystonia, who tested positive for N-methyl-D-aspartate receptor (NMDAR) antibodies in the cerebrospinal fluid (CSF). 1,2 The 23-year-old developed tremulous cervical and laryngeal dystonia over 5 months, without any other neurological or psychiatric features. Brain magnetic resonance imaging showed T2 hyperintensities in the basal ganglia, midbrain, and pons.…”

“…In this issue, two groups report the cases of two young women with isolated (cranio‐) cervical dystonia, who tested positive for N‐methyl‐D‐aspartate receptor (NMDAR) antibodies in the cerebrospinal fluid (CSF) 1,2 …”