Isolated Chloroma: The Effect of Early Antileukemic Therapy

Imrie, Kevin; Kovacs, Michael J.; Selby, Debbie; Lipton, Jeffrey H.; Patterson, Bruce; Pantalony, Dominic; Poldre, P; Ngan, Bo–Yee; Keating, Armand

doi:10.7326/0003-4819-123-5-199509010-00005

Cited by 188 publications

(121 citation statements)

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“…Stem cell transplantation has also been used as intensified postremission therapy in second CR. 15,16 Patients with chromosome abnormalities appeared to have lower CR rates, shorter survival and FFS in our study. Although these differences did not reach statistical significance (Figure 3) -probably because of the small numbers of patients -an abnormal marrow karyotype may indicate a poor prognosis with GS and more intensive therapy may be required for these patients.…”

Section: Figurementioning

confidence: 69%

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Outcome in patients with nonleukemic granulocytic sarcoma treated with chemotherapy with or without radiotherapy

et al. 2003

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Section: Figurementioning

confidence: 69%

“…Imrie et al 15 have reported that antileukemic chemotherapy at the time of diagnosis is associated with a significantly lower probability of developing AML and with prolonged survival. Stem cell transplantation has also been used as intensified postremission therapy in second CR.…”

Section: Figurementioning

confidence: 99%

Outcome in patients with nonleukemic granulocytic sarcoma treated with chemotherapy with or without radiotherapy

et al. 2003

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“…The majority of studies have concluded that all patients with GS should receive mastectomy or lumpectomy plus standard systemic chemotherapy (3,4,23,24). Imrie et al (25) reported that the overall survival was longer in chemotherapy-treated patients compared with those who did not receive chemotherapy. The case presented in the current study was treated with lumpectomy and systemic chemotherapy, and no local recurrence was identified in the breast one year later.…”

Section: Discussionmentioning

confidence: 99%

Granulocytic sarcoma of the breast: A case report

Huang

Zhou

2015

Oncology Letters

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Abstract. Granulocytic sarcoma (GS) is an unusual type of tumor composed of immature cells outside the bone marrow. The disease exhibits a correlation with acute myeloid leukemia and other myeloproliferative disorders. Although it can invade a number of areas of the body, the involvement of the breast is uncommon. The present study reports the case of a 58-year-old female with a mildly tender lump in the left breast that had been apparent for one year. Available diagnostic techniques, including ultrasound, magnetic resonance imaging and mammography, were systematically used to determine a diagnosis of GS, and lumpectomy and systemic chemotherapy were performed. The patient was satisfied with the result of no local recurrence at the one year follow-up examination. The present study discusses the clinical and pathological characteristics of the present case of GC.

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“…However, primary granulocytic sarcoma respond well to local treatment such as surgery or radiotherapy. Primary granulocytic sarcoma usually progress to AML within a year with a median survival of 22 months [11]. Therefore, systemic chemotherapy against leukemia should be utilized after completion of treatment of local condition.…”

Section: Discussionmentioning

confidence: 99%