Isolated cerebral vasculitis associated with rheumatoid arthritis

Pons, Núria Caballol; Montalà, Núria; Valverde, José; Brell, Marta; Ferrer, Isidre; Martínez-Yélamos, Sergio

doi:10.1016/j.jbspin.2010.02.030

Cited by 44 publications

(11 citation statements)

References 17 publications

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“…Neurological manifestations in patients with RA can be due to inflammatory central nervous system lesions. They have been described traditionally in seropositive patients with long-standing, active and erosive RA, with subcutaneous nodules and extra-articular manifestations [11]. In our case, the RA was seropositive, active and erosive but the patient had no extra-articular signs especially no subcutaneous nodules.…”

Section: Discussionmentioning

confidence: 59%

Cerebral rheumatoid vasculitis: a case report

et al. 2012

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IntroductionCentral nervous system involvement in rheumatoid arthritis is infrequent. The most frequent neurological manifestations of rheumatoid arthritis are peripheral neuropathy and cervical spinal cord compression due to subluxation of the cervical vertebrae. Cerebral rheumatoid vasculitis is an uncommon and serious complication which can be life-threatening.Case presentationA 52-year-old North African Tunisian Caucasian woman presented with a six-week history of headache. She had suffered seropositive and destructive rheumatoid arthritis for nine years without any extra-articular complications. Magnetic resonance imaging of the brain with the T2 sequence showed high-intensity signal images at the frontal and parietal cortico-subcortical junction suggesting hemispheric vasculitis.ConclusionsCerebral vasculitis is an infrequent complication in rheumatoid arthritis which is associated with high morbidity and in some cases can be life-threatening. Early assessment and a high index of suspicion to recognize such complications are essential in managing these patients.

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Section: Discussionmentioning

confidence: 59%

Cerebral rheumatoid vasculitis: a case report

et al. 2012

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“…Other system involvement includes heart, bowel and kidney which are much less common but can lead to significant morbidity and mortality, including myocardial infarction, bowel ischaemia and renal failure 12 13…”

Section: Discussionmentioning

confidence: 99%

Rheumatoid vasculitis: early presentation of rheumatoid arthritis

2016

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Rheumatoid vasculitis is a rare and late complication of rheumatoid arthritis and may affect small-to-medium-sized vessels. Here, we report a case of a 49-year-old man who presented with amaurosis fugax in the left eye, symmetric polyarthritis, Raynaud's symptoms and paraesthesia in both lower extremities. The patient subsequently experienced right foot drop, nail fold infracts and gangrene of his right second toe. He was found to have a high titre of rheumatoid factor and treatment with rituximab and high dose of corticosteroids led to significant improvement of his symptoms. This is rare case describing the early onset of rheumatoid vasculitis in a patient with rheumatoid arthritis.

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“…Even in recent years, RV remains a serious complication of RA and is associated with significant mortality [21]. …”

Section: Pathogenesismentioning

confidence: 99%

New insight into the rheumatoid vasculitis

Cojocaru

Cohocaru

Chico

2015

Romanian Journal of Internal Medicine

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Vasculitis in rheumatoid arthritis (rheumatoid vasculitis, RV) has a heterogeneous clinical presentation that includes skin disorders, neuropathy, eye symptoms and systemic inflammation. Rheumatoid vasculitis is an unusual complication of longstanding, severe rheumatoid arthritis (RA).While RA affects the body's joints, vasculitis is a condition in which blood vessels become inflamed. Rheumatoid vasculitis occurs in approximately 2 to 5% of patients who have RA. The blood vessels most often involved are arteries that bring blood to the skin, nerves, and internal organs. Veins can also be involved. Rheumatoid vasculitis is skin condition that is a typical feature of RA, presenting as peripheral vascular lesions that are localized (purpura, cutaneous ulceration, and gangrene of the distal parts of the extremities). The cause of RV is unknown, but given the prominence of immune components and the pathologic changes in involved blood vessels, an autoimmune process is suggested. Compared to other forms of vasculitis, there has been relatively little research in recent years on the specific entity of RV. There is some evidence that the incidence of RV has decreased over the past several decades, perhaps because of a better treatment of the underlying RA. In the present review, we discuss the clinical features, laboratory tests, the pathogenesis of RV.

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Isolated cerebral vasculitis associated with rheumatoid arthritis

Cited by 44 publications

References 17 publications

Cerebral rheumatoid vasculitis: a case report

Cerebral rheumatoid vasculitis: a case report

Rheumatoid vasculitis: early presentation of rheumatoid arthritis

New insight into the rheumatoid vasculitis

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