Isocoumarin derivatives from the sea squirt-derived fungus penicillium stoloniferum QY2-10 and the halotolerant fungus penicillium notatum B-52

Xin, Zhi Hong; Tian, Li; Zhu, Tian Jiao; Wang, Wen Liang; Du, Lin; Fang, Yuchun; Gu, Qian Qun; Zhu, Wei

doi:10.1007/bf02978830

Cited by 52 publications

(33 citation statements)

References 5 publications

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“…The known compounds (8-13; Scheme 2) were identified as fumiquinazoline J (8), [20] 3Ј-O-acetylthymidine (9), [21] 6,8-dihydroxy-3,4,5-trimethylisocoumarin (10), [22] dihydrocitrinone (11), [23] dihydrocitrinin (12), [24] and pretrichodermamide A (13) [25] by comparison of their 1 H and 13 C NMR spectroscopic data and mass spectrometric data with published data. This is the first time that compounds 8 and 13 have been isolated from a sponge-associated fungus; previous studies reported their isolation from Aspergillus fumigatus and Trichoderma sp.…”

Section: Resultsmentioning

confidence: 99%

Alkaloids from the Sponge‐Associated Fungus Aspergillus sp.

et al. 2012

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Seven new alkaloids including tryptoquivaline K (1) and fumiquinazolines K-P (2-7), bearing a rare 1-aminocyclopropane-1-carboxylic acid residue, together with six known compounds (8-13), were isolated from the fungus Aspergillus sp. obtained from the Mediterranean sponge Tethya aurantium. The structures of the new compounds were determined by extensive analysis by 1D and 2D NMR spectroscopy and mass spectrometry. The absolute configurations of tryptoquivaline K (1) and fumiquinazolines K and L (2, 3) were determined by TDDFT ECD calculations of their solution conformers, and the configurational assignment of the related fu-

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Section: Resultsmentioning

confidence: 99%

Alkaloids from the Sponge‐Associated Fungus Aspergillus sp.

et al. 2012

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“…The relative configuration of 1 was further determined by nuclear Overhauser effect spectroscopy (NOESY) spectrum. Its relative configurations were identical to those of 1-acetonyl-7-carboxyl-6,8-dihydroxy-3,4,5-trimethylisochroman (Xin et al 2007) according to their identical nuclear Overhauser effect (NOE). data, and correspondingly, its absolute configurations were deduced as 1R,1 0 R,3R,3 0 R,4S,4 0 S. Thus, the structure of 1 was elucidated as shown and named penicitrinol G.…”

Section: Introductionmentioning

confidence: 98%

“…These NMR data of 1 were similar to those of citrinin (Clark et al 2006), 1-acetonyl-7-carboxyl-6,8-dihydroxy-3,4,5-trimethylisochroman (Xin et al 2007) and other citrinin derivatives (Xu et al 2006), which suggested that 1 had a citrinin skeleton. Detailed comparison of the NMR data of 1 and 1-acetonyl-7-carboxyl-6,8-dihydroxy-3,4,5-trimethylisochroman (Xin et al 2007) showed that the only obvious difference between them was the disappearance of one methyl (-COCH 3 ) in 1. Combined with the molecular formula of C 29 H 34 O 11 , the above NMR suggested that 1 should be a citrinin dimer.…”

Section: Introductionmentioning

confidence: 99%

Three new polyketides from marine-derived fungusPenicillium citrinumSCSGAF 0167

Sun

Zhang

Zheng³

et al. 2013

Natural Product Research

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Three new polyketides penicitrinol G (1), penicitrinol H (2) and 2,11-dihydroxy-1-methoxycarbonyl-9-carboxylxanthone (3) together with one known cathepsin B inhibitor chrysophanol (4) were isolated from a culture broth of marine-derived fungus Penicillium citrinum SCSGAF 0167. Their structures were determined by spectroscopic methods. Compound 4 exhibited inhibitory activity against cathepsin B with IC 50 value of 1.7 mM.

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“…Within our screening program for isolation of microorganisms containing bioactive components [4], astrain of Aspergillus terreus was isolated from the rhizosphere soil of tomato. The title compound, dihydrocitrinone, was first described by [5], and elucidated on the basic of spectroscopic analysis [6,7]. Herein, the compound was re-isolated from the solid fermentation culture of the soil-borne fungus A. terreus.…”

Section: Discussionmentioning

confidence: 99%