We make an analysis of three -loop effects of the strong coupling constant in the study of masses and decay constants of the heavy-flavour pseudo-scalar mesons (PSM) D, $$D_s$$
D
s
, B, $$B_s,$$
B
s
,
$$B_c$$
B
c
, $$\eta _c$$
η
c
and $$\eta _b$$
η
b
in a non-relativistic QCD potential model using Dalgarno’s perturbation theory (DPT). The first order mesonic wavefunction is obtained using Dalgarno’s perturbation theory. The three-loop effects of strong coupling constant are included in the wave function in co-ordinate space and then used to examine the static and dynamic properties of the heavy-flavour mesons for 2S and 3S higher states. The results are compared with the other models available and are found to be compatible with available experimental values. In V-scheme, the three-loop effects on masses and decay constants of heavy-flavour mesons show a significant result.