Ischemic Stroke in Young Adults and Preexisting Psychiatric Disorders

Chiu, Yu‐Chuan; Bai, Ya Mei; Su, Tung Ping; Chen, Tzeng Ji; Chen, Mu Hong

doi:10.1097/md.0000000000001520

Cited by 15 publications

(9 citation statements)

References 39 publications

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“…Bipolar disorder and hypertension significantly increase the risk of stroke [ 127 , 128 ] and according to some results this effect is stronger than the effect of unipolar MDD on the risk of stroke [ 129 ].…”

Section: Similarities and Differences Between Essential Hmentioning

confidence: 99%

Is Mania the Hypertension of the Mood? Discussion of A Hypothesis

Rihmer

Gonda²,

Döme³

2017

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Beyond both being biphasic/bidirectional disorders (hypo)mania and essential hypertension share a surprising number of similarities and an overlap between their genetics, biological background, underlying personality and temperamental factors, precipitating factors, comorbidity and response to treatment, indicating a possibly partially shared biological background. Based on theoretical knowledge, similarities related to characteristics, manifestation and course, and the results of pharmacological studies related to the effects and side effects of pharmacotherapies used in the treatment of these two distinct disorders, the authors outline a hypothesis discussing the similar origins of these two phenomena and thus mania being the hypertension of mood in memory of Athanasios Koukopoulos, one of the greatest researchers and theoreticists of mania of all time.

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Section: Similarities and Differences Between Essential Hmentioning

confidence: 99%

Is Mania the Hypertension of the Mood? Discussion of A Hypothesis

Rihmer

Gonda²,

Döme³

2017

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“…141 patients in this study were Hindus, 8 were Muslims and 1 patient was Christian. Amongst the patients who were Hindus, the most common psychiatric illness was MDD (49), Followed by Generalized anxiety disorder (20), psychotic disorder (3) and social phobia (2).…”

Section: Resultsmentioning

confidence: 99%

“…As seen in table 4, among the 150 patients, most of the patients had ischemic stroke (139), while the rest had hemorrhagic stroke (11). Patients with ischemic stroke had MDD (48) as the most common psychiatric illness followed by GAD generalized anxiety disorder (20), psychotic disorder (3) and social phobia (2).…”

Section: Resultsmentioning

confidence: 99%

Study of Psychiatric Morbidity Among the Survivors of Cerebrovascular Stroke at a Tertiary Care Centre

Gupte¹,

Raj²

2021

mvpjms

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Introduction: According to World Health Organization (WHO), cerebrovascular stroke is the second leading cause of death and disability all over the world. Infarct alters brain function which leads to neuropsychiatric sequela. Psychiatric morbidities are common in stroke-survivor cohorts and are associated with increased morbidity and mortality. Aims and Objectives: The present study was conducted in a tertiary care hospital to understand the different psychiatric morbidities in patients with cerebrovascular accidents (stroke). Material and Methods: 150 stroke survivors were included in the study after they satisfied the eligibility criteria. Mini International Neuropsychiatric Interview (MINI) 7.0.0 was applied to diagnose the psychiatric illness in the patients. Results: Out of 150 patients 79 patients (52.66%) had psychiatric illness. Out of the 150 patients, 50 patients (33.33%) had Major Depressive Disorder, 24 patients (16%) had Generalized Anxiety Disorder (GAD), 3 patients (2%) were diagnosed with psychotic disorder whereas 2 Patients (1.33%) had social phobia. Out of which 50 patients (33.33%) were having Major Depressive Disorder (MDD), 24 patients (16%) were having Generalized Anxiety Disorder, 3 patients (2%) were having psychotic disorder and 2 Patients (1.33%) were having Social phobia. Most of the patients had ischemic type of stroke (133 patients) , left sided lesion (88 patients) being the most common. Conclusion: Major depressive disorder was the most common psychiatric illness followed by generalized anxiety disorder. The psychiatric illness was not associated with type of stroke and side of lesion.

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“…[38][39][40][41] A better understanding of barriers to evidence-based stroke care in patients with psychiatric comorbidities is particularly critical because mental illness in and of itself confers an increased lifetime risk of stroke. [42][43][44] Moreover, patients with psychiatric conditions represent a disproportionately high number of stroke patients under the age of 45, 45 even after accounting for demographic and clinical factors. Thus, addressing treatment inequities in patients with psychiatric conditions is an important component of preventing long-term disability from stroke.…”

Section: Discussionmentioning

confidence: 99%

Patients with stroke and psychiatric comorbidities have lower carotid revascularization rates

et al. 2019

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ObjectiveWe investigated whether mental illness is associated with lower rates of carotid endarterectomy (CEA)/carotid artery stenting (CAS) after stroke due to carotid stenosis.MethodsIn this retrospective cross-sectional study, ischemic stroke cases due to carotid stenosis were identified in the 2007–2014 Nationwide (National) Inpatient Sample. Psychiatric conditions were identified by secondary ICD-9-CM diagnosis codes for schizophrenia/psychoses, bipolar disorder, depression, anxiety, or substance use disorders. Using logistic regression, we tested the association between psychiatric conditions and CEA/CAS, controlling for demographic, clinical, and hospital factors.ResultsAmong 37,474 included stroke cases, 6,922 (18.5%) had a psychiatric comorbidity. The presence of any psychiatric condition was associated with lower odds of CEA/CAS (adjusted odds ratio [OR] 0.84, 95% confidence interval [CI] 0.78–0.90). Schizophrenia/psychoses (OR 0.72, 95% CI 0.55–0.93), depression (OR 0.83, 95% CI 0.75–0.91), and substance use disorders (OR 0.73, 95% CI 0.65–0.83) were each associated with lower odds of CEA/CAS. The association of mental illness and CEA/CAS was dose-dependent: compared to patients without mental illness, patients with multiple psychiatric comorbidities (OR 0.74, 95% CI 0.62–0.87) had lower odds of CEA/CAS than those with only one psychiatric comorbidity (OR 0.86, 95% CI 0.79–0.92; p value for trend <0.001).ConclusionThe odds of carotid revascularization after stroke is lower in patients with mental illness, particularly those with schizophrenia/psychoses, depression, substance use disorders, and multiple psychiatric diagnoses.

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Ischemic Stroke in Young Adults and Preexisting Psychiatric Disorders

Cited by 15 publications

References 39 publications

Is Mania the Hypertension of the Mood? Discussion of A Hypothesis

Is Mania the Hypertension of the Mood? Discussion of A Hypothesis

Study of Psychiatric Morbidity Among the Survivors of Cerebrovascular Stroke at a Tertiary Care Centre

Patients with stroke and psychiatric comorbidities have lower carotid revascularization rates

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