“…The pathophysiology for isolated spontaneous CCA dissection is not well known but it seems to be multifactorial, including familial and genetic predispositions and other risk factors, such as hypertension, hyperlipidemia, infections, and uncommon connective tissue diseases [3,6]. In the current case, the patient was already diagnosed with hypertension and hyperlipidemia, but the CCA dissection occurred spontaneously without any traumatic events even after regular medications and work-ups on the cardiac status.…”