2014
DOI: 10.1053/j.semperi.2014.03.001
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Ischemic placental disease: A unifying concept for preeclampsia, intrauterine growth restriction, and placental abruption

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Cited by 101 publications
(112 citation statements)
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“…In line with our positive findings for placental disorders, we found a positive association between TTP and IPD, a syndrome that includes preeclampsia, intrauterine growth restriction, and placental abruption (21, 22). These three obstetrical conditions have been hypothesized to represent distinct clinical manifestations of the same underlying disease process at varying gestational ages (21).…”
Section: Discussionsupporting
confidence: 90%
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“…In line with our positive findings for placental disorders, we found a positive association between TTP and IPD, a syndrome that includes preeclampsia, intrauterine growth restriction, and placental abruption (21, 22). These three obstetrical conditions have been hypothesized to represent distinct clinical manifestations of the same underlying disease process at varying gestational ages (21).…”
Section: Discussionsupporting
confidence: 90%
“…There was only a weak association between fertility treatment and PTB risk (RR=1.05, 95% CI: 0.72, 1.54), which explains why control for fertility treatment had little effect on the association between TTP and PTB. When we further controlled for ischemic placental disease (IPD), which accounts for up to 50% of medically-indicated PTB (21), the RR for TTP (≥12 versus <3 cycles) and medicallyindicated PTB was 1.05 (95% CI: 0.48, 2.31). The overall association between TTP (≥12 versus <3 cycles) and PTB became stronger when we used a more stringent definition of PTB (<36 weeks’ gestation: IRR=2.25, 95% CI: 1.09, 4.65; <35 weeks’ gestation: IRR=4.20, 95% CI: 1.48, 11.9).…”
Section: Resultsmentioning
confidence: 99%
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