Ischemic Colitis After Routine Colonoscopy

Omar, Haniza; Siglin, Scott; Fine, Marc

doi:10.1111/den.12489

Cited by 6 publications

(3 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The etiology underlying colonoscopy-related CI has not been fully elucidated but, in agreement with other authors, the main cause seems to be barotrauma [ 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 ]. The pressure generated by the insufflated gas on the colonic wall would favor a hyperextension of it, which induces a reduction in total blood flow and a reduction in the arteriovenous oxygen gradient in the colonic wall, as already demonstrated in several experimental studies [ 13 ].…”

Section: Discussionsupporting

confidence: 66%

“…However, we cannot exclude other possible suggested etiologies such as temporary twist mesocolon resulting in an extreme traction of the colonic wall which can reduce blood flow as well as repeated trauma to the colonic wall resulting in damage to the arterial microcirculation [ 10 , 13 , 14 ]. In addition, there are numerous possible predisposing conditions such as decrease of intravascular volume resulting from fasting and preparation as the prolonged duration of the procedure [ 1 , 5 , 16 , 17 ].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Transmural Colonic Infarction after Routine Colonoscopy in a Young Patient without Risk Factors

Zizzo

Ruiz

Ugoletti

et al. 2016

Case Rep Gastroenterol

View full text Add to dashboard Cite

Colonoscopy is one of the most widely used procedures in medical practice for the diagnosis and treatment of many benign and malignant diseases of the colorectal tract. Colonscopy has become the reference procedure for screening and surveillance of colorectal cancer. The overall rate of adverse events is estimated to be about 2.8 per 1,000 procedures, while complications requiring hospitalization are about 1.9 per 1,000 colonoscopies. Mortality from all causes and colonoscopy-specific mortality are estimated to be 0.07 and 0.007%, respectively. An exceptional fearsome postcolonoscopy complication is colon ischemia (CI); only few cases have been reported worldwide. We present the case of a 43-year-old woman who presented to the emergency department complaining of abdominal pain; fever and rectal bleeding appeared 12 h after a voluntary ‘screening’ colonoscopy. She had no risk factors for CI. Her laboratory tests showed alterations in inflammatory markers and a computed tomography scan showed a circumferential thickening in the left colon and free fluid in the abdomen. After 12 h of observation and conservative therapy, the clinical state of the patient worsened with the rising of signs of peritonitis. Laparoscopy showed that colon infarction extended from the distal third of the transverse colon to the proximal rectum. Laparotomy, resection of the pathological colon and terminal colostomy were performed. The specimen examined confirmed an extended ischemic colitis and transmural infarction on the antimesocolic side, in the absence of a vasculitis. The patient underwent recanalization after 8 months. CI after colonoscopy is a rare and alarming complication that must be known and taken into account in the differential diagnosis of symptomatic cases after colonoscopy, particularly in patients with known risk factors. The diagnosis is mainly based on clinical data, imaging and especially endoscopy. Treatment is almost always conservative but, in some cases in which the pathological process appears irreversible, surgery becomes mandatory.

show abstract

Section: Discussionsupporting

confidence: 66%

Section: Discussionmentioning

confidence: 99%

Transmural Colonic Infarction after Routine Colonoscopy in a Young Patient without Risk Factors

Zizzo

Ruiz

Ugoletti

et al. 2016

Case Rep Gastroenterol

View full text Add to dashboard Cite

show abstract

“…About half of cases are due to arterial embolism originating from the heart, while the rest are attributed to arterial thrombosis (associated with atherosclerosis), venous thrombosis (linked to coagulation disorders), and non-occlusive ischemia (caused by factors like hypovolemia, hypotension, and reduced cardiac output) [1,11]. Furthermore, ischemic colitis has been linked to specific drugs, such as cocaine [12] and tegaserod [13], as well as colonoscopy procedures [14]. Studies have also reported associations between ischemic colitis and coronary artery disease, as well as end-stage renal disease requiring dialysis [15][16][17].…”

Section: Introductionmentioning

confidence: 99%

The Global Burden of Vascular Intestinal Disorders in 204 Countries and Territories From 1990 to 2019: Global Burden of Diseases Study

Jiang,

Cai,

et al. 2023

Int J Public Health

View full text Add to dashboard Cite

Objectives: Assess the prevalence, mortality, and disability-adjusted life years (DALYs) of vascular intestinal disorders (VID) from 1990 to 2019.Methods: This study conducted a secondary data analysis utilizing the Global Burden of Diseases Study 2019. The prevalence, mortality and DALYs of VID were analyzed by sex, age and socio-demographic index (SDI), respectively. Analyses were performed by using R software.Results: Globally, the number of prevalent VID cases increased from 100,158 (95% uncertainty interval: 89,428–114,013) in 1,990–175,740 (157,941–198,969) in 2019. However, the age-standardized rates (ASR) of VID prevalence declined from 2.47 (95% uncertainty interval: 2.24–2.76) per 100,000 population to 2.21 (1.98–2.48) per 100,000 population between 1990 and 2019. Furthermore, the ASR of mortality also decreased from 1990 to 2019. Between 1990 and 2019, the regions with high and high-middle level exhibited the highest diseases burden.Conclusion: Globally, the diseases burden associated with VID demonstrated a decline from 1990 to 2019. However, concerted efforts are still required to enhance measures to combat VID within countries categorized as high and high-middle SDI.

show abstract