Is Universal Pediatric Lipid Screening Justified?

Gillman, Matthew W.; Daniels, Stephen R.

doi:10.1001/jama.2011.2012

Cited by 55 publications

(20 citation statements)

References 8 publications

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“…This finding has been cited as part of the debate as to whether universal pediatric lipid screening was justified [22-24]. Universal cholesterol screening is now recommended for all children between 9 and 11 years of age [25], a recommendation facilitated by CARDIAC's school-based screening method for the detection of familial hypercholesterolemia.…”

Section: Researchmentioning

confidence: 99%

The Coronary Artery Risk Detection in Appalachian Communities (CARDIAC) Project: An 18 Year Review

Elliott

Lilly

Murphy

et al. 2018

CPR

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Background The Coronary Artery Risk Detection in Appalachian Communities (CARDIAC) Project is a chronic disease risk factor surveillance, intervention, and research initiative aimed at combating the unacceptably high prevalence of heart disease, diabetes, and other chronic illnesses in West Virginia. Objectives and Methods The school-based public health project identifies health risk factors in children, educates families, informs primary care physicians, and provides resources to schools to help improve population health, beginning with children. Results and Conclusion Details regarding methodology, results, and conclusions derived from this unique public health initiative that has screened over 200,000 children are the subject of this 18-year review.

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Section: Researchmentioning

confidence: 99%

The Coronary Artery Risk Detection in Appalachian Communities (CARDIAC) Project: An 18 Year Review

Elliott

Lilly

Murphy

et al. 2018

CPR

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“…[97][98][99] Hypoxemia in bronchiolitis Hospital admissions for children with bronchiolitis have significantly increased since 1980, a period coinciding with increased use of pulse oximetry, yet mortality from bronchiolitis during the same time period has been unchanged. 13,100 Oxygen saturation changes as small as 2% significantly increase a physician' s decision for admission, and the diagnosis of hypoxemia by continuous pulse oximetry prolongs hospitalization, but there is no evidence that supplemental oxygen for transient desaturations benefits children.…”

Section: Gastroesophageal Refluxmentioning

confidence: 99%

Overdiagnosis: How Our Compulsion for Diagnosis May Be Harming Children

et al. 2014

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Overdiagnosis occurs when a true abnormality is discovered, but detection of that abnormality does not benefit the patient. It should be distinguished from misdiagnosis, in which the diagnosis is inaccurate, and it is not synonymous with overtreatment or overuse, in which excess medication or procedures are provided to patients for both correct and incorrect diagnoses. Overdiagnosis for adult conditions has gained a great deal of recognition over the last few years, led by realizations that certain screening initiatives, such as those for breast and prostate cancer, may be harming the very people they were designed to protect. In the fall of 2014, the second international Preventing Overdiagnosis Conference will be held, and the British Medical Journal will produce an overdiagnosis-themed journal issue. However, overdiagnosis in children has been less well described. This special article seeks to raise awareness of the possibility of overdiagnosis in pediatrics, suggesting that overdiagnosis may affect commonly diagnosed conditions such as attention-deficit/hyperactivity disorder, bacteremia, food allergy, hyperbilirubinemia, obstructive sleep apnea, and urinary tract infection. Through these and other examples, we discuss why overdiagnosis occurs and how it may be harming children. Additionally, we consider research and education strategies, with the goal to better elucidate pediatric overdiagnosis and mitigate its influence.

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“…24 The pediatric approach to lipid screening over the past several decades has focused on selective screening, meaning screening those with a family history of early atherosclerotic events and/or high cholesterol or those at risk for early atherosclerosis. [25][26][27] However, multiple studies have demonstrated that selective screening is insufficient in the United States to identify lipid disorders in children, as it misses 30% to 50% of those with high LDL 28,29 and may be particularly ineffective in disadvantaged populations.…”

Section: Identifying Fhmentioning

confidence: 99%

Familial hypercholesterolemia in children and adolescents: A clinical perspective

Ferranti

2015

Journal of Clinical Lipidology

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Is Universal Pediatric Lipid Screening Justified?

Cited by 55 publications

References 8 publications

The Coronary Artery Risk Detection in Appalachian Communities (CARDIAC) Project: An 18 Year Review

The Coronary Artery Risk Detection in Appalachian Communities (CARDIAC) Project: An 18 Year Review

Overdiagnosis: How Our Compulsion for Diagnosis May Be Harming Children

Familial hypercholesterolemia in children and adolescents: A clinical perspective

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