2011
DOI: 10.1136/gut.2011.239301.179
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* IS Triticum monococcum a coeliac-safe wheat? A phase II, single blind, cross-over study on the effect of acute administration on intestinal permeability

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“…An in vivo blind crossover study on the effect of a single dose of gluten of T. monococcum in patients with coeliac disease failed to demonstrate clinical adverse events and changes in intestinal permeability . However, when selected coeliac patients were fed for 60 consecutive days with daily fixed doses of baked products prepared from T. monococcum flour, all clinical, serological and histological criteria evidenced a toxic effect of einkorn gluten .…”
Section: Adverse Reactionsmentioning
confidence: 99%
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“…An in vivo blind crossover study on the effect of a single dose of gluten of T. monococcum in patients with coeliac disease failed to demonstrate clinical adverse events and changes in intestinal permeability . However, when selected coeliac patients were fed for 60 consecutive days with daily fixed doses of baked products prepared from T. monococcum flour, all clinical, serological and histological criteria evidenced a toxic effect of einkorn gluten .…”
Section: Adverse Reactionsmentioning
confidence: 99%
“…An in vivo blind crossover study on the effect of a single dose of gluten of T. monococcum in patients with coeliac disease failed to demonstrate clinical adverse events and changes in intestinal permeability. 124 However, when selected coeliac patients were fed for 60 consecutive days with daily fixed doses of baked products prepared from T. monococcum flour, all clinical, serological and histological criteria evidenced a toxic effect of einkorn gluten. 125 Although more complete studies testing several einkorn accessions over a broader range of patients are welcome, the available information indicates that einkorn, like its related species, is not suitable for coeliac patients.…”
Section: Adverse Reactionsmentioning
confidence: 99%