The COVID-19 crisis has disrupted traditional trade connections, significantly altering the global trade landscape. This served as a crucial stress test for international trade and regional integration blocs, challenging trade regionalization. Given these new challenges, we propose the concept of regional integration resilience, defined as the capacity of an integration bloc to mitigate the adverse impact of the pandemic on intraregional trade and minimize the immediate reduction of trade within that bloc. With the fortification of supply chains and greater economic interconnection within the integrating economies, our hypothesis is that regional economic integration could serve as a buffer against the negative consequences of the COVID-19 pandemic. Specifically, we have utilized fixed-effects instrumental variable regression applied to the augmented gravity model to analyze quarterly observations from January 2018 to December 2020. To gauge the influence of being in a trade bloc during the COVID-19 crisis, we introduced interaction terms (participation in a regional trade agreement and COVID-19 parameters) into the model. The findings suggest that the pandemic markedly and adversely impacted bilateral trade. Interestingly, the weight of the COVID-19 pandemic had a more pronounced effect on trade flows compared to its severity. Despite the anticipated positive effects of regional integration on intraregional trade due to its static and dynamic effects, overall, we did not observe any stabilizing influence of regional economic integration. There was no evidence that regional integration contributed to alleviating the negative effects on trade during a pandemic or fostering higher trade resilience within regional trade agreements. However, the impact of regional trade integration may vary across different integration blocs. Among the six integration blocs analyzed, two demonstrated a significant positive influence on trade during the pandemic -the European Union and the United States-Mexico-Canada Agreement (formerly the North American Free Trade Agreement).